Method of inhibiting osmotic water flow

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United States of America Patent

PATENT NO 4959355
SERIAL NO

07025959

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Abstract

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This invention provides a method of inhibiting osmotic water flow across mammalian cell membranes which involves contacting the water channels of the cell membranes with an effective amount of a glucose transport blocker or of digitonin so as to inhibit osmotic water flow across the membranes. Additionally, this invention provides a method of treating a subject afflicted with a condition associated with abnormal osmotic water flow across cell membranes which comprises administering to the subject an effective amount of a glucose transport blocker or of digitonin so as to contact the water channels of the subject's cell membranes and inhibit osmotic water flow across the membranes.

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Patent Owner(s)

Patent OwnerAddress
TRUSTEES OF COLUMBIA UNIVERSITY THE A CORP OF NYWEST 116 STREET & BROADWAY NEW YORK NY 10027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fischbarg, Jorge New York, NY 2 17
Koniarek, Jan P Briarcliff Manor, NY 2 26
Liebovitch, Larry S Long Island City, NY 2 18

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