Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same
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United States of America Patent
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Oct 16, 1990
Grant Date -
N/A
app pub date -
Mar 21, 1988
filing date -
Mar 27, 1987
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A compound of the formula: ##STR1## wherein R.sup.1 is aryl optionally substituted with a substituent selected from the group consisting of halogen and halo(lower)alkyl; lower alkyl or cyclo(lower)alkyl; and R.sup.2 is hydrogen or lower alkyl, or R.sup.1 and R.sup.2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted with a substituent selected from the group consisting of lower alkyl and esterified carboxy, R.sup.3 is hydrogen or lower alkyl, and R.sup.4 is lower alkyl, and its pharmaceutically acceptable salt, a process for the preparation thereof and pharmaceutical composition comprising the same.
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