Boron analogs of amino acid/peptide protease inhibitors

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United States of America Patent

PATENT NO 4963655
SERIAL NO

07199891

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Abstract

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A method of inhibiting protease activity, growth, and colony formation in mammalian tumor cells by boronic acid analogs of amino acids, dipeptides and tripeptides. A method of coupling a boronic acid analog of an amino acid to other N-protected amino acids or N-protected dipeptides and compositions formed from the coupled products.

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Patent Owner(s)

  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ames, Matthew M Rochester, MN 8 163
Kinder, David H Rochester, MN 4 153

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