Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini
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United States of America Patent
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Jan 1, 1991
Grant Date -
N/A
app pub date -
Jul 18, 1985
filing date -
Jul 19, 1984
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to novel oligonucleotides, the process for their preparation and their biological uses as mediators of the action of interferon. The oligonucleotides according to the invention have the formula: ##STR1## in which Y and T are identical or different and represent particularly O, S, Z and W are identical or different and represent particularly O, S, one at least of the elements Y and Z being different from oxygen, X represents particularly --CHOHCH.sub.2 OH, .SIGMA. is a whole number equal to or greater than 2, A represents adenine or one of its derivatives. These oligonucleotides have antiviral use.
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