Importance

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Abstract

New alkylthiobenzimidazole derivatives are described which belong to the class of formula: ##STR1## wherein R.sub.1 and R.sub.2 each represent a 1-3 carbon atom alkyl radical or they may form with the adjacent nitrogen atom, an optionally substituted heterocyclic ring, X represents a hydrogen atom or methyl radical n is 1 or 2 R.sub.3 represents a 4-6 carbon atom alkoxyalkyl radical, a 7 or 8 carbon atom arylalkyl radical or a 5 or 6 carbon atom cycloalkyl radical with the exception that R.sub.3 may not be an arylalkyl radical when R.sub.1 and R.sub.2 each represent a 1-3 carbon atom alkyl radical R.sub.4 and R.sub.5 may be the same or different and each represent a hydrogen atom or a 1-2 carbon atom alkyl or they, attached at the positions 5 and 6 of the benzimidazole nucleus, may form together the ring ##STR2## The compounds (I) possess interesting antihistaminic and anti-allergic activities.

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First Claim