Tissue processing apparatus

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 4985206
SERIAL NO

07250929

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A tissue or like processing method involving application of liquids to carrier-mounted material, e.g. a thin tissue section mounted on a microscope slide (10), is characterized by disposing a channel-defining element (1) adjacent to the carrier (10) to form an assembly providing an enclosure (11) for the material on the carrier. The enclosure (11) has an inlet (13) and an outlet (14) and has capillary dimensions. The assembly is disposed with the inlet (13) above the outlet (14) and liquid introduced into the inlet fills the enclosure and is retained in contact with the material on the carrier by surface tension effect. Further liquid introduced to the inlet (13) displaces the first liquid progressively to the outlet (14). A sequence of liquids can thus be brought successively into contact with the material with minimum wastage, by feeding the liquids successively to the inlet (13) of an assembly. A support for a plurality of assemblies to permit concurrent operations upon a set of material samples is disclosed, and a machine for automated processing, e.g. immunostaining, of a batch of tissue samples is also disclosed.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
Shandon Scientific LimitedCHESHIRE3

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bowman, David J Manchester, GB2 14 162
Cosgrove, Raymond F Wallasey, GB2 2 127
Evans, Robert Liverpool, GB2 65 947
Male, Terence P Helsby, GB2 2 127

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 4790640 Laboratory slide 144 1985
 
Technicon Instruments Corporation (1)
* 4629703 Automated analytical system 53 1983
 
Whale Scientific, Inc. (1)
* 4501496 Specimen slide for analysis of liquid specimens 44 1982
 
ADI DIAGNOSTICS INC. (1)
* 4883760 Device for performing enzyme immunoassays 21 1988
 
VENTANA MEDICAL SYSTEMS, INC. (1)
* 4731335 Method for treating thin samples on a surface employing capillary flow 100 1985
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (4)
* 5508198 Storage and incubation apparatus for temperature sensitive medical test samples 1 1994
* 2005/0019,898 Fluid mixing in low aspect ratio chambers 32 2004
* 2006/0093,520 Automated molecular pathology apparatus having fixed slide platforms 1 2005
* 2011/0167,930 INFORMATION NOTIFICATION SAMPLE PROCESSING SYSTEM AND METHODS OF BIOLOGICAL SLIDE PROCESSING 8 2011
 
American Registry of Pathology (4)
* 5958341 Apparatus for efficient processing of tissue samples on slides 87 1996
6703247 Apparatus and methods for efficient processing of biological samples on slides 47 1998
7598036 Apparatus and methods for efficient processing of biological samples on slides 1 2005
* 2010/0112,577 APPARATUS AND METHODS FOR EFFICIENT PROCESSING OF BIOLOGICAL SAMPLES ON SLIDES 0 2009
 
CTYOLOGIX CORPORATION (1)
6673620 Fluid exchange in a chamber on a microscope slide 68 2000
 
BIOPATH AUTOMATION, L.L.C. (14)
7179424 Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor 32 2004
7722810 Apparatus and methods for automated handling and embedding of tissue samples 7 2004
* 2005/0226,770 Apparatus and methods for automated handling and embedding of tissue samples 33 2004
7776274 Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefore, and methods therefor 10 2005
* 2005/0147,538 Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefore, and methods therefor 23 2005
* 2007/0166,834 APPARATUS AND METHOD FOR HARVESTING AND HANDLING TISSUE SAMPLES FOR BIOPSY ANALYSIS 17 2006
8877146 Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor 0 2007
* 2007/0104,618 CASSETTE FOR HANDLING AND HOLDING TISSUE SAMPLES DURING PROCESSING, EMBEDDING AND MICROTOME PROCEDURES, AND METHODS THEREFOR 12 2007
8383067 Biopsy support with sectionable resilient cellular material 1 2007
* 2010/0167,334 SYSTEMS AND METHODS FOR PROCESSING TISSUE SAMPLES FOR HISTOPATHOLOGY 9 2009
8734735 Tissue cassette for automated handling and embedding of tissue samples 4 2011
8034292 Apparatus and methods for automated handling and embedding of tissue samples 1 2011
* 2011/0182,783 TISSUE CASSETTE FOR AUTOMATED HANDLING AND EMBEDDING OF TISSUE SAMPLES 1 2011
* 2011/0165,615 APPARATUS AND METHODS FOR AUTOMATED HANDLING AND EMBEDDING OF TISSUE SAMPLES 1 2011
 
BioPath Automaction, L.L.C. (1)
* 2005/0084,425 Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor 7 2004
 
Shandon Scientific Limited (1)
D330085 Immunostaining workstation 4 1989
 
ALESSI TECHNOLOGIES, LLC (2)
9341548 System and method for biological specimen mounting 1 2015
9719897 System and method for biological specimen mounting 0 2016
 
VENTANA MEDICAL SYSTEMS, INC. (25)
6296809 Automated molecular pathology apparatus having independent slide heaters 189 1999
* 6352861 Automated biological reaction apparatus 164 1999
6582962 Automated molecular pathology apparatus having independent slide heaters 107 2000
7425306 Slide heater 13 2001
6943029 Automated biological reaction apparatus 127 2002
* 2002/0072,122 Automated biological reaction apparatus 26 2002
6827901 Automated biological reaction apparatus 97 2002
7270785 Automated molecular pathology apparatus having fixed slide platforms 35 2002
7303725 Automated high volume slide staining system 58 2003
* 2004/0002,163 Automated high volume slide staining system 36 2003
7378055 Automated molecular pathology apparatus having fixed slide platforms 50 2003
* 2003/0203,493 Automated molecular pathology apparatus having fixed slide platforms 33 2003
* 2004/0052,685 Automated molecular pathology apparatus having independent slide heaters 24 2003
7470541 Automated biological reaction apparatus 22 2004
* 2005/0153,453 Automated biological reaction apparatus 16 2004
7615371 Method and apparatus for treating a biological sample with a liquid reagent 11 2004
7468161 Automated high volume slide processing system 39 2005
* 2005/0186,114 Automated high volume slide processing system 34 2005
8663991 Automated high volume slide processing system 1 2005
* 2005/0250,211 Automated high volume slide processing system 30 2005
7404927 Automated molecular pathology apparatus having fixed slide platforms 32 2005
8048373 Automated high volume slide staining system 4 2007
* 2009/0253,592 METHOD AND APPARATUS FOR TREATING A BIOLOGICAL SAMPLE WITH A LIQUID REAGENT 1 2009
* 2011/0215,081 METHODS AND APPARATUSES FOR HEATING SLIDES CARRYING SPECIMENS 5 2009
9528918 Automated high volume slide processing system 0 2013
 
VISION BIOSYSTEMS LIMITED (4)
9346053 Method and apparatus for fluid dispensation, preparation and dilution 1 2004
* 2010/0191,382 Method and apparatus for fluid dispensation, preparation and dilution 4 2004
* 2005/0270,642 Microscope slide cover with integrated reservoir 13 2005
* 2010/0178,668 BIOLOGICAL REACTION APPARATUS WITH DRAINING MECHANISM 11 2010
 
APPLIED BIOSYSTEMS, LLC (4)
* 5364790 In situ PCR amplification system 65 1993
* 5675700 Assembly system for in situ per amplification 25 1995
* 5527510 In situ PCR amplification system 26 1995
* 5681741 In situ PCR amplification system 49 1995
 
Alessi Technologies, Inc. (2)
9057671 System and method for biological specimen mounting 2 2014
9041922 System and method for biological specimen mounting 3 2014
 
ROCHE NIMBLEGEN, INC. (4)
7223363 Method and system for microfluidic interfacing to arrays 58 2002
7235400 Laminated microarray interface device 15 2002
* 2002/0192,701 Laminated microarray interface device 9 2002
* 2004/0037,739 Method and system for microfluidic interfacing to arrays 108 2002
 
LEICA BIOSYSTEMS MELBOURNE PTY LTD (3)
8337786 Microscope slide cover with integrated reservoir 4 2009
9029154 Fill fluid for biological reaction apparatus with draining mechanism 0 2010
9128300 Microscope slide cover with integrated reservoir 0 2012
 
American Registry of Pathology Armed Forces Institute of Pathology (1)
* 2005/0238,534 Apparatus and methods for efficient processing of biological samples on slides 3 2005
 
TECRAInternational Pty Ltd. (1)
* 7374951 System and apparatus for use in detecting microorganisms 1 2002
 
3M INNOVATIVE PROPERTIES COMPANY (1)
7771986 System and apparatus for use in detecting microorganisms 0 2007
 
NICHIREI BIOSCIENCES INC. (1)
9719896 Aid for filling liquid, and method for filling liquid 0 2014
 
DAKOCYTOMATION DENMARK A/S (1)
7758809 Method and system for pretreatment of tissue slides 3 2009
 
DAKO DENMARK A/S (40)
* 5947167 Dispensing assembly with interchangeable cartridge pumps 117 1997
6183693 Random access slide stainer with independent slide heating regulation 132 1998
* 6096271 Random access slide stainer with liquid waste segregation 130 1998
6180061 Moving platform slide stainer with heating elements 106 1998
6541261 Method using a slide stainer with independent slide heating regulation 84 2000
7718435 Automated slide stainer with slide housing 13 2000
6783733 Random access slide stainer with independent slide heating regulation 70 2001
* 2002/0054,830 Random access slide stainer with independent slide heating regulation 5 2001
7318913 Fluid exchange in a chamber on a microscope slide 40 2003
7648678 Method and system for pretreatment of tissue slides 13 2003
* 2005/0064,535 Method and apparatus for pretreatment of tissue slides 58 2003
8257968 Method and apparatus for automatic staining of tissue samples 9 2003
8216512 Apparatus for automated processing biological samples 1 2003
7960178 Enhanced scheduling sample processing system and methods of biological slide processing 12 2003
7400983 Information notification sample processing system and methods of biological slide processing 60 2003
* 2006/0088,928 Method and apparatus for automatic staining of tissue samples 58 2003
* 2006/0046,298 Enhanced scheduling sample processing system and methods of biological slide processing 32 2003
* 2006/0045,806 Apparatus for automated processing biological samples 45 2003
9778273 Isolated communication sample processing system and methods of biological slide processing 0 2003
8298815 Systems and methods of sample processing and temperature control 7 2003
* 2006/0172,426 Systems and methods of sample processing and temperature control 28 2003
* 2006/0088,940 Isolated communication sample processing system and methods of biological slide processing 57 2003
* 2004/0191,128 Slide stainer with heating 32 2004
7217392 Random access slide stainer with independent slide heating regulation 26 2004
7553672 Random access slide stainer with independent slide heating regulation 17 2007
* 2007/0281,364 Random access slide stainer with independent slide heating regulation 2 2007
8173068 Fluid exchange in a chamber on a microscope slide 1 2007
* 2008/0056,954 Fluid exchange in a chamber on a microscope slide 0 2007
7937228 Information notification sample processing system and methods of biological slide processing 12 2008
* 2008/0241,876 Information notification sample processing system and methods of biological slide processing 3 2008
8386195 Information notification sample processing system and methods of biological slide processing 9 2011
8394635 Enhanced scheduling sample processing system and methods of biological slide processing 11 2011
8529836 Apparatus for automated processing biological samples 4 2012
8663978 Method and apparatus for automatic staining of tissue samples 3 2012
8788217 Information notification sample processing system and methods of biological slide processing 2 2013
8673642 Enhanced scheduling sample processing system and methods of biological slide processing 4 2013
8784735 Apparatus for automated processing biological samples 0 2013
9599630 Method and apparatus for automatic staining of tissue samples 0 2014
8969086 Enhanced scheduling sample processing system and methods of biological slide processing 1 2014
9229016 Information notification sample processing system and methods of biological slide processing 0 2014
 
BIOGENEX LABORATORIES (2)
* 5439649 Automated staining apparatus 240 1993
* 5948359 Automated staining apparatus 159 1997
 
CELERUS DIAGNOSTICS, INC. (8)
8178350 Method and apparatus for automated rapid immunohistochemistry 3 2006
8058010 Enhanced fluidic method and apparatus for automated rapid immunohistochemistry 17 2006
8034610 Parallel processing fluidic method and apparatus for automated rapid immunohistochemistry 3 2006
7838283 Wicking cassette method and apparatus for automated rapid immunohistochemistry 17 2006
* 2009/0004,691 Enhanced Fluidic Method and Apparatus for Automated Rapid Immunohistochemistry 21 2006
* 2008/0286,753 Wicking Cassette Method and Apparatus for Automated Rapid Immunohistochemistry 18 2006
* 2008/0213,804 Parallel Processing Fluidic Method and Apparatus for Automated Rapid Immunohistochemistry 8 2006
* 2008/0194,034 Method And Apparatus For Automated Rapid Immunohistochemistry 11 2006
 
NEXELL THERAPEUTICS INC. (2)
* 7754155 Devices and methods for isolating target cells 0 2002
* 2003/0175,850 Devices and methods for isolating target cells 7 2002
 
3DHistech KFT. (1)
9625478 Automated integrated slide-processing system 0 2014
 
SAKURA FINETEK U.S.A., INC. (21)
* 5695942 Automated histo-cytochemistry apparatus and encapsulation system for processing biological materials 24 1995
* 5965454 Automated histo-cytochemistry apparatus and encapsulation system for processing biological materials 43 1997
7501283 Fluid dispensing apparatus 16 2003
* 2005/0035,156 Fluid dispensing apparatus 17 2003
7767152 Reagent container and slide reaction retaining tray, and method of operation 6 2006
* 2006/0171,857 Reagent container and slide reaction and retaining tray, and method of operation 8 2006
7744817 Manifold assembly 61 2006
* 2006/0169,719 Manifold assembly 10 2006
9518899 Automated reagent dispensing system and method of operation 0 2006
* 2006/0173,575 Automated reagent dispensing system and method of operation 6 2006
8459509 Fluid dispensing apparatus 0 2006
* 2007/0272,710 Fluid dispensing apparatus 17 2006
8329120 Microtome sectionable biopsy support for orienting tissue samples 4 2010
* 2010/0184,127 MICROTOME SECTIONABLE BIOPSY SUPPORT FOR ORIENTING TISSUE SAMPLES 12 2010
8752732 Fluid dispensing system 1 2011
8932543 Automated staining system and reaction chamber 2 2011
8580568 Traceability for automated staining system 1 2011
8796038 Method for orienting tissue samples on a microtome sectionable biopsy support 1 2012
9914124 Fluid dispensing apparatus 0 2013
9005980 Traceability for automated staining system 0 2013
9016526 Fluid dispensing system 0 2014
 
Perceptive Scientific Instruments, Inc. (1)
* 5367401 Microscope slide rotary stage 51 1990
 
BOEHRINGER MANNHEIM GMBH (1)
* 5830413 Device for processing slide-mounted samples 18 1996
 
World Properties, Inc. (1)
* 7238535 Test cell for evaluating phosphor 1 2004
 
SAKURA FINETEK JAPAN KABUSHIKI KAISHA (ALSO TRADING AS SAKURA FINETEK JAPAN CO., LTD.) (1)
* 5338358 Apparatus for dyeing tissues 66 1992
 
PROHISTO, LLC (1)
* 2008/0081,368 Method and apparatus that increases efficiency and reproducibility in immunohistochemistry and immunocytochemistry 0 2007
 
DCS Innovative Diagnostik-Systeme Dr. Christian Sartori GmbH & Co. KG (2)
* 9176034 Object support retainer 0 2010
* 2012/0168,588 OBJECT SUPPORT RETAINER 0 2010
* Cited By Examiner