Glucose tolerance factor and method of making same
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United States of America Patent
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Jan 15, 1991
Issued Date -
N/A
app pub date -
Feb 14, 1990
filing date -
Nov 21, 1985
priority date (Note) -
Expired
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Abstract
A glucose tolerance factor which reduces blood sugar in mammals and is derived from yeast. The glucose tolerance factor can be isolated from autolyzed brewer's yeast extract by sequential fractionation on Sephadex G-75, Biogel P-6, Biogel P-2, to give a purified glucose tolerance factor. By further purification, a substantially purified glucose tolerance factor is obtained which is a quinoline derivative with a molecular ion at 174 by mass spectrometry.
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