Pharmaceutical formulation ensuring the transdermal absorption of the active ingredient and process for preparing same
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United States of America Patent
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Mar 5, 1991
Grant Date -
N/A
app pub date -
Feb 17, 1989
filing date -
Jun 22, 1987
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to a multilayer pharmaceutical formulation containing layers with various active ingredient content, a water-impermeable layer applied thereon and an adhesive layer ensuring the fixation to the body surface of the pharmaceutical formulation, which comprises: a silicone rubber layer directly contacting with the skin surface and ensuring the zero order kinetics of the dissolution of the active ingredient; as well as a multilaminated silicone rubber matrix comprising one or more layers(s) with various active ingredient content.
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