Method for enhancing the lowering of plasma cholesterol levels
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United States of America Patent
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Mar 5, 1991
Grant Date -
N/A
app pub date -
Nov 21, 1988
filing date -
Nov 21, 1988
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The instant invention is directed to a method for enhancing the lowering of plasma cholesterol level in a subject in need thereof which comprises the time-controlled administration of a nontoxic therapeutically effective amount of an HMG-CoA reductase inhibitor to said subject which surprisingly affords an equivalent or improved reduction of plasma cholesterol levels while significantly reducing the amount of HMG-CoA reductase inhibitor circulating in the bloodstream of the subject as compared to the same parameters when the oral administration of a conventional rapid release dosage form is utilized.
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