Thermally reversible polyurethane hydrogels and cosmetic, biological and medical uses

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United States of America Patent

PATENT NO 5000955
SERIAL NO

07559513

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Thermally reversible polyurethane hydrogels are formed by adding water to a gel forming hydrophilic polyurethane polymer produced by reacting under anhydrous conditions a non-aromatic organic diisocyanate with a glycol component in an NCO/OH mole weight ratio of from about 0.900/1 to about 0.980/1, the glycol component having a number average molecular weight of from about 1000 to 3500 wherein the percentage by weight of the diisocyanate in the reaction mixture is from about 7% to about 20%. The hydrogels are solids at room temperature but liquify at higher temperatures such as body temperature and therefore are useful as carriers for the protection, delivery and sustained release of a variety of active agents including pharmaceuticals, cosmetics, living cells and organisms.

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Patent Owner(s)

Patent OwnerAddress
TYNDALE PLAINS-HUNTER LTDPRINCETON NJ

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gould, Francis E Princeton, NJ 19 969
Johnston, Christian W Neshanic Station, NJ 15 813
Seems, George E Pennington, NJ 3 242

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