Determining the concentration of water soluble species in biological fluid
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United States of America Patent
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Mar 19, 1991
Grant Date -
N/A
app pub date -
Sep 18, 1989
filing date -
Sep 18, 1989
priority date (Note) -
Expired
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Abstract
Correcting an initial measurement of the concentration of a first water soluble species dissolved in a water-based component of a biological fluid that also includes a second water soluble species and a volume occupying component, the initial measurement having been taken using an original sample of the fluid that had been diluted by an amount of additional aqueous solution to form a diluted sample is disclosed; the concentration of the second water soluble species is measured in an undiluted sample of the biological fluid to obtain a direct concentration and is measured using a diluted sample of the fluid to obtain an indirect concentration, and the initial measurement of concentration of the first species is adjusted based on a combination of the direct and indirect concentration determinations of the second species.
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