Calcification mitigation of bioprosthetic implants
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United States of America Patent
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Mar 26, 1991
Issued Date -
N/A
app pub date -
Apr 18, 1989
filing date -
Feb 17, 1989
priority date (Note) -
Expired
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Abstract
Calcification resistant bioprosthetic implants are made from tanned biological materials, such as porcine heart valves, bovine pericardium, human dura mater or the like, which has been impregnated with a calcification-mitigating effective amount of a ferric and/or stannic salt. The impregnated biological materials and processes are particularly advantageous for the preparation of bioprosthetic heart valves. These implants have been found to be highly resistant to calcification in vivo.
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