Artificial pancreatic perfusion device
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United States of America Patent
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-
Mar 26, 1991
Grant Date -
N/A
app pub date -
Aug 25, 1989
filing date -
Aug 25, 1989
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A device which serves as an artificial pancreas comprises a hollow fiber having an inner diameter of about 5 mm which is surrounded by islets of Langerhans enclosed in a housing. The islets are suspended in a semi-solid matrix which ensures desired distribution of the cells about the hollow fiber. The hollow fiber and suspended islets are enclosed in a housing which further aids the desired distribution of islets about the hollow fiber. The hollow fiber has a porosity which selectively allows passage of substances having a molecular weight of less than about 100,000 Daltons. The semi-solid matrix in which the islets are embedded and suspended is formed of an appropriate supporting material such as alginate or agar.
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