Non-covalent antibody-anthracycline immunocomplexes
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United States of America Patent
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Apr 2, 1991
Grant Date -
N/A
app pub date -
Sep 24, 1986
filing date -
Sep 24, 1986
priority date (Note) -
Expired
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Abstract
A composition comprising a non-covalent immunocomplex of an anthracycline agent and an antibody selected to bind a target antigen and enhance the cytotoxicity of the anthracycline agent is disclosed. In accordance with the invention, the efficacy of an anthracycline as an anti-tumor agent for use in in vivo therapy is enhanced by administering to a patient a non-covalent immunocomplex provided herein.
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