Reagent and method for determining activity of retroviral protease
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United States of America Patent
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Apr 30, 1991
Grant Date -
N/A
app pub date -
Dec 28, 1989
filing date -
Dec 28, 1989
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel fluorogenic substrates for retroviral protease, e.g. HIV protease, having the chemical structure X--Thr--Ile--Nle--Phe(Y)--Gln--Arg--NH.sub.2 wherein X is a fluorogenic group and Y is an acceptor for the fluorogenic group, and their use in a fluorometric method for the determination of retroviral protease is disclosed.
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