Anti-infective and antithrombogenic medical articles and method for their preparation
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United States of America Patent
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May 7, 1991
Issued Date -
N/A
app pub date -
Mar 21, 1990
filing date -
Jan 18, 1989
priority date (Note) -
Expired
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Abstract
An anti-infective medical article has chlorhexidine bulk distributed throughout a polyurethane base layer and may have a coating layer on the base layer. The coating layer may be chlorhexidine permeated into the surface or it may be an antibiotic, antithrombogenic agent or a polymeric surface layer laminated onto the base layer. The invention includes a method for preparing the article wherein a homogeneous melt of polymer and chlorhexidine is prepared by twin screw compounding and the melt is extruded to give a medical article having bulk distributed chlorhexidine.
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