Membrane, process and system for isolating virus from solution
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United States of America Patent
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-
May 21, 1991
Grant Date -
N/A
app pub date -
May 10, 1990
filing date -
May 10, 1990
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A composite membrane and process utilizing the membrane which is capable of selectively removing particles such as viral particles from a solution such as a protein solution is provided. The membrane comprises a porous membrane substrate, a surface skin having ultrafiltration separation properties and an intermediate porous zone between the substrate and the skin which intermediate zone has an average pore size smaller than that of the substrate. The intermediate zone is free of voids which break the skin and which directly fluid communicate with the substrate. The composite is capable of a log reduction value of at least 3 (99.9% removal) of particles selectively from solution.
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