Method of producing fine coated pharmaceutical preparation
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United States of America Patent
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-
May 21, 1991
Grant Date -
N/A
app pub date -
Aug 18, 1989
filing date -
Aug 22, 1989
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A method of producing a fine coated pharmaceutical preparation, which includes cooling fine liquid droplets composed of a liquid medium, a drug dissolved or suspended in the liquid medium, and as required, a binder to a temperature of not higher than the freezing point of the liquid medium to form frozen particles of the drug and as required the binder, adjusting the particle sizes of the fine frozen particles, mixing the fine frozen particles with a fine powder of a coating material having a particle diameter smaller than the particles at a temperature higher than the freezing point of the liquid medium to cause the fine powder of the coating material to adhere to the surfaces of the particles, and then removing the liquid medium from the resulting coated particles.
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