Filtration media with low protein adsorbability
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United States of America Patent
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May 28, 1991
Issued Date -
N/A
app pub date -
Dec 7, 1989
filing date -
Dec 23, 1986
priority date (Note) -
Expired
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Abstract
A porous polymeric medium having a low affinity for amide group-containing and adjuvant-containing materials is provided comprising a porous polyvinylidene difuoride substrate and a surface-modifying polymeric material having a low affinity for amide group-containing materials formed in situ at and covalently bonded to the surface of the porous polyvinylidene difluoride substrate, the surface-modifying polymeric material being formed from a monofunctional monomer having at least one hydroxyl group. Another embodiment that provides a porous polymeric medium having a low affinity for amide group-containing materials employs a supplemental monomer in combination with the monofunctional monomer having at least one hydroxyl group to form the surface-modifying polymeric material. The supplmental monomer or comonomer used is one which, when formed as a homopolymer, has a high affinity for amide group-containing materials.
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