Method and composition for treating hyperproliferative skin diseases using 6-aminopurine cytokinins
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United States of America Patent
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Jun 4, 1991
Grant Date -
N/A
app pub date -
Jun 8, 1989
filing date -
Jun 8, 1989
priority date (Note) -
Expired
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Abstract
It has been discovered that 6-(substituted amino)purine cytokinins, such as kinetin, induce differentiation, and consequently reduce or eliminate the abnormally high rate of proliferation, of hyperproliferating cells associated with hyperproliferative skin diseases, such as psoriasis. Thus, the present invention provides methods and compositions for treating hyperproliferative skin diseases in mammals, particularly such diseases associated with hyperproliferating epidermal cells in humans, by administering to the hyperproliferating cells associated with such a disease, in the skin of a mammal suffering therefrom, a differentiation-inducing effective amount of a 6-(substituted amino)purine cytokinin.
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