Hydrogenated rapamycin derivatives
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United States of America Patent
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Jun 11, 1991
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N/A
app pub date -
Aug 14, 1990
filing date -
Aug 14, 1990
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Expired
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Abstract
A derivative of rapamycin where one, two, or three of the double bonds at the 1-,3-, or 5-positions of rapamycin have been reduced to the corresponding alkane, or a pharmaceutically acceptable salt thereof, which by virtue of its antifungal activity is useful in treating fungal infections. ##STR1##
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