Pharmaceutical microemulsions
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United States of America Patent
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Jun 11, 1991
Grant Date -
N/A
app pub date -
Aug 13, 1985
filing date -
Aug 13, 1985
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method for parenteral administration of fat-soluble pharmaceuticals and vitamins using microemulsions is disclosed. The microemulsions are comprised of a naturally occurring amphipatic substance and a hydrophobic lipid along with the active ingredient, are size selected for 300-1000 .ANG. pseudomicelles, and permit safe intravenous injection of the active ingredient. Levels of the active ingredient in the various lipoprotein fractions of serum appear to mimic the natural distribution of the administered drug if taken orally.
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