Methods for imaging atherosclerotic plaque
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United States of America Patent
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Jun 25, 1991
Grant Date -
N/A
app pub date -
Apr 6, 1989
filing date -
Apr 6, 1989
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention pertains to a method of imaging atherosclerotic plaque using radiolabeled monoclonal antibodies that are specific for activated platelets or activated endothelial cells. The method is capable of determining the site of endothelial injury. This method involves the administration of a platelet-specific labeled monoclonal antibody or antibody fragment to a patient. The antibody is allowed to accumulate at the plaque site and the plaque is then scanned with a photoscanner. The detected signals are then converted into an image of the plaque.
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