DNA probe which reveals a hypervariable region on human chromosome 16
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United States of America Patent
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Jun 25, 1991
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N/A
app pub date -
Sep 30, 1987
filing date -
May 4, 1987
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Abstract
A DNA probe p79-2-23 is homologous to at least a portion of a hypervariable DNA region located on chromosome 16q22.fwdarw.q24 in the human genome. The DNA region displays a restriction fragment length polymorphism when digested with certain restriction endonucleases. Unrelated individuals display unique fragment patterns on Southern blots probed with p79-2-23. The probe can be used to produce a genetic 'fingerprint' for establishing human identity, determining engraftment of bone marrow transplants, determining parentage, and otherwise mapping genes.
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