Use of photodynamic compositions for cytotoxic effects
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United States of America Patent
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Jul 2, 1991
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N/A
app pub date -
Dec 27, 1988
filing date -
Dec 27, 1988
priority date (Note) -
Expired
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Abstract
Hematopoietic cells are selectively eliminated by cytotoxic agents which rely upon light activation. The cytotoxic agents are joined to ligands, particularly sugars, specific for myeloid monocyte and lymphocytic lineages. Further specificity can be achieved by limiting the light target. The method and compositions find particular use in organ transplants and arthritis.
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