Mucoadhesive carrier for delivery of therapeutical agent
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United States of America Patent
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Sep 10, 1991
Grant Date -
N/A
app pub date -
Jun 3, 1988
filing date -
Jun 3, 1988
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A mucoadhesive carried suitable for a therapeutic agent is disclosed. This carrier allows controlled release of the therapeutic agent via mucosal tissue. The mucoadhesive carrier comprises a Monolithic polymer matrix that is anhydrous but hydratable, and amorphous fumed silica. The silica enhances the mucoadhesive properties of the carrier. An optional water-insoluble barrier film or layer can be secured to the polymer matrix to provide a non-adhering face.
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