Inhibition of mineral deposition by phosphorylated and related polyanionic peptides
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United States of America Patent
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Sep 24, 1991
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N/A
app pub date -
Apr 7, 1989
filing date -
Apr 7, 1989
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Expired
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Abstract
A poly-amino acid compound capable of inhibiting mineral deposition, which has the structure: poly (X).sub.m (Y).sub.n where each X independently is aspartate, glutamate, glutamine, asparagine, or anionic derivatives of these amino acids, or phosphoserine, each Y independently is a phosphorylated amino acid such as phosphoserine, phosphohomoserine, phosphotyrosine, phosphothreonine, phosphoglutamine, phosphoasparagine, or mixtures of these residues, m is 2 to 150, n is 1 to 3, and n+m is .gtoreq.5, and salts of these peptides.
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