Lysis of fibrin blood clots with urokinase and pro-urokinase
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United States of America Patent
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Oct 8, 1991
Issued Date -
N/A
app pub date -
May 2, 1989
filing date -
Oct 3, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The thrombolytic effect of the plasminogen activator pro-urokinase is improved synergistically by the co-administration of urokinase. The two components may be administered sequentially or simultaneously, and if simultaneously, either separately or as a mixture. Preferably an initial bolus injection of urokinase is followed by an infusion of pro-urokinase.
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