Galenical forms of corticoids for administration perlingually and sublingually and process for their preparation
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United States of America Patent
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Oct 29, 1991
Grant Date -
N/A
app pub date -
Oct 7, 1988
filing date -
Oct 8, 1987
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
In these new galenical forms the corticoid is contained, in strictly controlled and reproducible amounts, in solid supports provided for an extended release of the active ingredient perlingually and sublingually. The corticoid is preferably methylprednisolone. The galenical forms can be prepared as follows: dissolving the corticoid in a solvent, preparing dilutions with different concentrations, fractionating each of these dilutions into subdilutions, impregnating by multi-impregnation or fractionated impregnation a pharmaceutically acceptable solid support with each of the subdilutions, each of said impregnation stages being followed by a drying in forced air dried at a temperature not more than 35.degree. C.
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