Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
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United States of America Patent
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Nov 19, 1991
Issued Date -
N/A
app pub date -
Sep 29, 1989
filing date -
Sep 30, 1988
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Targeting substance-diagnostic/therapeutic agent conjugates joined by stabilized Schiff base or hydrazone linkages are disclosed. In addition, slow release carrier-drug pharmaceuticals are described. The diagnostic and therapeutic conjugates and pharmaceuticals of the present invention provide certain advantages relating to in vivo administration, including controlled release of the active agent at a target site.
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