Method of preparing oral dosage forms with a granulating composition
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United States of America Patent
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Dec 17, 1991
Issued Date -
N/A
app pub date -
Oct 4, 1990
filing date -
Nov 3, 1988
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rapid disintegration or dispersion are important factors. It is useful for tablets containing ingredients which are difficult to compress and is particularly useful for formulating swallowable tablets of a single non-soluble ingredient such as calcium carbonate. Disintegration times are markedly decreased.
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