Muramyl peptide derivatives and immunoregulating compositions containing them
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United States of America Patent
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Dec 24, 1991
Grant Date -
N/A
app pub date -
Feb 26, 1990
filing date -
Mar 3, 1989
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Muramyl peptide derivatives of the formula: ##STR1## wherein 'Ala' is ##STR2## 'isoGln' is ##STR3## R.sup.1 is R.sub.3 O-- or ##STR4## (k is an integer from 8 to 12; q is an integer from 10 to 22) or R.sub.3 is ##STR5## (m is an integer from 11 to 17; n is an integer from 11 to 17)]; and R.sub.2 is hydrogen atom or --CO--(CH.sub.2).sub.p --CH.sub.3 (p is an integer from 8 to 22); which act on in vivo immunomechanism of human beings and livestock (in particular cells relevant immune responses) and are useful as imminoregulating agents.
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