US Patent No: 5,087,244

Number of patents in Portfolio can not be more than 2000

Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen

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Abstract

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A method and catheter for use in practicing the method are provided by which a highly concentrated medication or chemotherapeutic agent can be applied locally under sufficient pressure to cause the medication or agent to penetrate into the localized tissue. The total volume of medication or agent is quite small, well below levels that might cause an adverse reaction in other parts of the body. The catheter includes a thin walled flexible balloon having a plurality of minute holes through which medication may flow at a low flow rate. The balloon is inflated with the medication under pressure and the flow rate of the order of a few ccs per minute is controlled by the minute holes in the balloon. In practicing the method of the invention, the balloon is selected such that its inflated diameter will correspond to or be slightly greater than the diameter of the lumen into which it is to be placed so that when the balloon is inflated, it will contact intimately the surface of the lumen. Inflation of the balloon with the medication will cause a thin film to spread between the balloon and the lumen, the film being maintained under a sufficient pressure to penetrate significantly the surrounding tissue with a high concentration of medication. The quantity of medication that ultimately flows free into the lumen is quite small and is insufficient to cause any other damage to the patient.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
C.R. BARD, INC.MURRAY HILL, NJ738

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barbere, Michael D Dunstable, MA 26 1121
King, Spencer L Atlanta, GA 1 294
Wolinsky, Harvey New York, NY 3 776

Cited Art Landscape

Patent Info (Count) # Cites Year
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (3)
4,323,071 Vascular guiding catheter assembly and vascular dilating catheter assembly and a combination thereof and methods of making the same 512 1980
4,782,834 Dual lumen dilatation catheter and method of manufacturing the same 175 1987
4,821,722 Self-venting balloon dilatation catheter and method 105 1987
 
BOSTON SCIENTIFIC SCIMED, INC. (1)
4,994,033 Intravascular drug delivery dilatation catheter 393 1989
 
Hanover; George (1)
4,327,721 Endotracheal tube with topical agent delivery system and method of using the same 87 1979
 
MEDTRONIC INTERVENTIONAL VASCULAR, INC. (1)
4,917,666 Steerable thru-lumen catheter 109 1988
 
Other [Check patent profile for assignment information] (6)
4,211,233 Urethral catheter 48 1978
4,437,856 Peritoneal catheter device for dialysis 107 1981
4,417,576 Double-wall surgical cuff 175 1982
4,423,725 Multiple surgical cuff 443 1982
4,636,195 Method and apparatus for removing arterial constriction 235 1985
4,693,243 Conduit system for directly administering topical anaesthesia to blocked laryngeal-tracheal areas 125 1986

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
ACCLARENT, INC. (40)
8,740,929 Spacing device for releasing active substances in the paranasal sinus 0 2002
8,317,816 Balloon catheters and methods for treating paranasal sinuses 4 2002
7,361,168 Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders 91 2004
7,720,521 Methods and devices for performing procedures within the ear, nose, throat and paranasal sinuses 21 2005
7,410,480 Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders 74 2005
8,114,113 Multi-conduit balloon catheter 4 2005
8,190,389 Adapter for attaching electromagnetic image guidance components to a medical device 5 2006
7,419,497 Methods for treating ethmoid disease 63 2006
8,702,626 Guidewires for performing image guided procedures 0 2006
8,439,687 Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices 5 2006
8,858,586 Methods for enlarging ostia of paranasal sinuses 0 2007
8,747,389 Systems for treating disorders of the ear, nose and throat 0 2007
8,118,757 Methods and devices for ostium measurement 0 2007
8,485,199 Methods and devices for protecting nasal turbinate during surgery 0 2007
8,146,400 Endoscopic methods and devices for transnasal procedures 14 2007
8,088,101 Devices, systems and methods for treating disorders of the ear, nose and throat 7 2007
8,123,722 Devices, systems and methods for treating disorders of the ear, nose and throat 13 2007
8,715,169 Devices, systems and methods useable for treating sinusitis 0 2007
8,172,828 Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures 14 2007
8,090,433 Methods and apparatus for treating disorders of the ear nose and throat 7 2007
8,080,000 Methods and apparatus for treating disorders of the ear nose and throat 11 2007
7,785,315 Methods for irrigation of ethmoid air cells and treatment of ethmoid disease 18 2007
8,142,422 Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat 19 2008
8,182,432 Corewire design and construction for medical devices 0 2008
8,864,787 Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis 0 2008
8,100,933 Method for treating obstructed paranasal frontal sinuses 5 2008
8,388,642 Implantable devices and methods for treating sinusitis and other disorders 7 2008
8,764,729 Frontal sinus spacer 0 2008
8,764,726 Devices, systems and methods useable for treating sinusitis 0 2009
8,414,473 Methods and apparatus for treating disorders of the ear nose and throat 14 2009
8,114,062 Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders 8 2009
8,425,457 Devices, systems and methods for diagnosing and treating sinusitus and other disorder of the ears, nose and/or throat 13 2009
8,828,041 Devices, systems and methods useable for treating sinusitis 0 2010
8,435,290 System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx 0 2010
8,852,143 Devices, systems and methods for treating disorders of the ear, nose and throat 0 2010
8,870,893 Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat 0 2010
8,764,709 Devices, systems and methods for treating disorders of the ear, nose and throat 0 2010
8,721,591 Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures 0 2012
8,764,786 Balloon catheters and methods for treating paranasal sinuses 0 2012
8,777,926 Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasel or paranasal structures 0 2013
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (37)
5,342,298 Automated fluid pressure control system 100 1992
5,415,637 Temporary stenting catheter with drug delivery capabilities 77 1993
5,611,775 Method of delivery therapeutic or diagnostic liquid into tissue surrounding a body lumen 142 1994
5,626,562 Drug delivery catheter 64 1994
5,865,794 Drug delivery catheter 19 1997
7,481,790 Vessel enlargement by arteriogenic factor delivery 1 2000
6,544,223 Balloon catheter for delivering therapeutic agents 242 2001
6,764,505 Variable surface area stent 294 2001
7,862,495 Radiation or drug delivery source with activity gradient to minimize edge effects 1 2001
6,706,013 Variable length drug delivery catheter 150 2001
7,169,178 Stent with drug coating 69 2002
7,115,299 Balloon catheter for delivering therapeutic agents 19 2003
7,258,891 Stent mounting assembly and a method of using the same to coat a stent 20 2003
7,169,173 Composite stent with regioselective material and a method of forming the same 24 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 62 2003
7,563,324 System and method for coating an implantable medical device 37 2003
7,674,493 Method of making a variable surface area stent 1 2004
7,553,377 Apparatus and method for electrostatic coating of an abluminal stent surface 15 2004
7,077,860 Method of reducing or eliminating thrombus formation 27 2004
7,297,159 Selective coating of medical devices 9 2004
7,648,727 Methods for manufacturing a coated stent-balloon assembly 5 2004
7,632,307 Abluminal, multilayer coating constructs for drug-delivery stents 9 2004
7,867,547 Selectively coating luminal surfaces of stents 0 2005
8,003,156 Rotatable support elements for stents 7 2006
7,658,966 Balloon catheter for delivering therapeutic agents 7 2006
7,824,440 Stent with drug coating 3 2006
7,824,441 Stent with drug coating 3 2006
7,820,229 Method of coating a stent 3 2006
7,666,223 Stent with drug coating 4 2006
8,197,879 Method for selectively coating surfaces of a stent 0 2007
7,604,700 Stent mandrel fixture and method for selectively coating surfaces of a stent 1 2007
8,119,184 Method of making a variable surface area stent 1 2010
8,293,367 Nanoshells on polymers 1 2011
8,741,379 Rotatable support elements for stents 0 2011
8,637,110 Rotatable support elements for stents 0 2011
8,596,215 Rotatable support elements for stents 0 2011
8,465,789 Rotatable support elements for stents 0 2011
 
BOSTON SCIENTIFIC SCIMED, INC. (24)
5,304,121 Drug delivery system making use of a hydrogel polymer coating 517 1991
5,397,307 Drug delivery PTCA catheter and method for drug delivery 164 1993
5,415,636 Dilation-drug delivery catheter 91 1994
5,514,092 Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration 133 1994
6,136,258 Method of forming a co-extruded balloon for medical purposes 65 1995
5,716,410 Temporary stent and method of use 100 1995
5,797,877 Medical device balloons containing thermoplastic elastomers 192 1996
5,792,106 In situ stent forming catheter 60 1997
5,795,318 Method for delivering drugs to a vascular site 55 1997
6,132,824 Multilayer catheter balloon 60 1997
7,087,039 Perfusion balloon angioplasty catheter 1 1997
6,299,597 Percutaneous repair of cardiovascular anomalies and repair compositions 72 1997
6,086,556 Medical device balloons containing thermoplastic elastomers 53 1998
6,482,348 Method of forming a co-extruded balloon for medical purposes 38 2000
6,896,842 Medical device balloons containing thermoplastic elastomers 19 2000
7,613,503 Device with infusion holes for imaging inside a blood vessel 0 2002
8,317,747 Catheter for tissue dilation and drug delivery 1 2004
7,781,038 Medical device balloons containing thermoplastic elastomers 3 2004
7,371,257 Stent lining 11 2004
7,632,242 Catheter including a compliant balloon 7 2004
7,585,289 Co-extruded medical balloon 0 2005
8,021,329 Catheter including a compliant balloon 1 2009
8,540,668 Catheter including a compliant balloon 0 2011
8,669,360 Methods of converting amorphous drug substance into crystalline form 0 2011
 
MEDTRONIC, INC. (10)
5,112,303 Tumor access device and method for delivering medication into a body cavity 83 1991
5,324,261 Drug delivery balloon catheter with line of weakness 94 1992
5,370,614 Method for making a drug delivery balloon catheter 81 1993
5,893,840 Releasable microcapsules on balloon catheters 145 1996
6,551,290 Catheter for target specific drug delivery 49 2000
6,945,969 Catheter for target specific drug delivery 31 2000
6,510,348 Perfusion lead and method of use 6 2000
6,697,677 System and method for placing a medical electrical lead 40 2001
6,567,704 Medical electrical lead and method of use 31 2001
7,153,292 Catheter for target specific drug delivery 1 2004
 
W. L. GORE & ASSOCIATES, INC. (10)
5,752,934 Balloon catheter device 85 1995
5,868,704 Balloon catheter device 88 1996
6,120,477 Balloon catheter device 164 1997
7,892,201 Balloon catheter and method of mounting same 0 1999
6,923,827 Balloon catheter device 23 2002
8,460,240 Inflatable toroidal-shaped balloons 0 2006
7,785,290 Non-shortening high angle wrapped balloons 5 2006
8,597,566 Non-shortening wrapped balloon 0 2009
8,636,690 Catheter balloons with integrated non-distensible seals 0 2009
8,585,640 Non-shortening high angle wrapped balloons 0 2010
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (9)
8,603,530 Nanoshell therapy 0 2006
8,048,448 Nanoshells for drug delivery 1 2006
8,017,237 Nanoshells on polymers 3 2006
8,025,916 Methods for forming a composite stent with regioselective material 1 2006
8,048,441 Nanobead releasing medical devices 1 2007
8,277,868 Balloon catheter for delivering therapeutic agents 0 2009
8,440,090 Apparatus and method of making a variable stiffness multilayer catheter tubing 0 2010
8,592,036 Nanoshells on polymers 0 2012
8,808,342 Nanoshell therapy 0 2013
 
CORDIS CORPORATION (8)
5,213,576 Therapeutic porous balloon catheter 275 1991
6,146,358 Method and apparatus for delivery of therapeutic agent 142 1992
5,318,531 Infusion balloon catheter 121 1992
5,405,472 Method of making infusion balloon catheter 47 1993
5,674,198 Tandem balloon catheter 57 1995
5,823,996 Infusion balloon catheter 78 1996
5,833,659 Infusion balloon catheter 78 1996
6,616,650 Method and apparatus for delivery of therapeutic agent 36 2000
 
VENTION MEDICAL ADVANCED COMPONENTS, INC. (8)
5,286,254 Drug delivery apparatus and method 404 1992
5,282,785 Drug delivery apparatus and method 253 1992
5,498,238 Simultaneous angioplasty and phoretic drug delivery 141 1993
5,458,568 Porous balloon for selective dilatation and drug delivery 216 1993
5,628,730 Phoretic balloon catheter with hydrogel coating 349 1994
5,807,306 Polymer matrix drug delivery apparatus 311 1994
5,569,198 Microporous catheter 92 1995
5,800,392 Microporous catheter 265 1996
 
ANGIODYNAMICS, INC. (7)
7,585,836 Bi-lateral local renal delivery for treating congestive heart failure and for BNP therapy 2 2005
7,993,325 Renal infusion systems and methods 1 2005
7,766,961 Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens 7 2005
7,771,401 Selective renal cannulation and infusion systems and methods 3 2007
8,012,121 Method and apparatus for selective material delivery via an intra-renal catheter 3 2007
8,585,678 Method and apparatus for intra-aortic substance delivery to a branch vessel 0 2008
8,518,011 Sheath for use in peripheral interventions 0 2009
 
ATRIUM MEDICAL CORPORATION (7)
6,955,661 Expandable fluoropolymer device for delivery of therapeutic agents and method of making 69 1999
6,395,208 Method of making an expandable fluoropolymer device 48 1999
7,637,886 Expandable fluoropolymer device and method of making 4 2002
7,572,245 Application of a therapeutic substance to a tissue location using an expandable medical device 13 2004
8,021,331 Method of coating a folded medical device 1 2005
7,947,015 Application of a therapeutic substance to a tissue location using an expandable medical device 13 2007
8,308,684 Method of coating a folded medical device 0 2011
 
J.W. MEDICAL SYSTEMS LTD. (7)
5,571,086 Method and apparatus for sequentially performing multiple intraluminal procedures 224 1994
7,147,655 Balloon catheter for multiple adjustable stent deployment 44 2002
8,157,851 Apparatus and methods for deployment of multiple custom-length prostheses 2 2005
7,938,851 Devices and methods for operating and controlling interventional apparatus 10 2005
7,320,702 Apparatus and methods for deployment of multiple custom-length prostheses (III) 44 2005
8,147,536 Balloon catheter for multiple adjustable stent deployment 0 2009
8,142,487 Balloon catheter for multiple adjustable stent deployment 0 2009
 
LOCALMED, INC. (6)
5,279,565 Intravascular treatment apparatus and method 183 1993
5,609,574 Intravascular catheter with infusion array 72 1994
5,536,250 Perfusion shunt device and method 60 1994
5,562,620 Perfusion shunt device having non-distensible pouch for receiving angioplasty balloon 53 1995
5,713,860 Intravascular catheter with infusion array 72 1995
5,599,306 Method and apparatus for providing external perfusion lumens on balloon catheters 103 1995
 
MEDTRONIC AVE, INC. (6)
5,904,670 Catheters and methods for guiding drugs and other agents to an intended site by deployable grooves 49 1996
6,280,413 Thrombolytic filtration and drug delivery catheter with a self-expanding portion 163 1997
5,854,822 Miniature x-ray device having cold cathode 40 1997
6,108,402 Diamond vacuum housing for miniature x-ray device 44 1998
6,069,938 Method and x-ray device using pulse high voltage source 28 1998
6,958,059 Methods and apparatuses for drug delivery to an intravascular occlusion 32 2001
 
AD-TECH MEDICAL INSTRUMENT CORP. (4)
7,241,283 Method for intracranial catheter treatment of brain tissue 20 2003
7,465,292 Catheter system for intracranial treatment 4 2005
7,322,954 Catheter assembly for intracranial treatment using dual lumens 5 2005
7,255,686 Catheter assembly for intracranial treatment 4 2005
 
CYTORI THERAPEUTICS, INC. (4)
8,784,801 Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease 0 2011
8,691,216 Methods of using regenerative cells to promote wound healing 0 2012
8,883,499 Systems and methods for isolating and using clinically safe adipose derived regenerative cells 0 2012
8,771,678 Methods of using adipose tissue-derived cells in augmenting autologous fat transfer 0 2012
 
SCIMED LIFE SYSTEMS, INC. (4)
5,558,642 Drug delivery catheter 122 1994
5,716,340 Blood perfusion catheter 43 1996
6,409,716 Drug delivery 120 1997
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CARDIOVASCULAR DYNAMICS, INC. (3)
5,295,962 Drug delivery and dilatation catheter 137 1992
5,569,215 Low profile infusion catheter 33 1995
5,569,184 Delivery and balloon dilatation catheter and method of using 81 1995
 
EDWARDS LIFESCIENCES CORPORATION (3)
6,685,672 Multi-balloon drug delivery catheter for angiogenesis 9 2000
6,692,458 Intra-pericardial drug delivery device with multiple balloons and method for angiogenesis 50 2000
6,997,898 Multi-balloon drug delivery catheter for angiogenesis 12 2004
 
INTERSECT ENT, INC. (3)
7,547,323 Stent for irrigation and delivery of medication 15 2006
8,277,503 Stent for irrigation and delivery of medication 0 2009
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KENSEY NASH CORPORATION (3)
6,709,427 Systems and methods for delivering agents into targeted tissue of a living being 30 1999
7,594,900 Systems and methods for delivering agents into targeted tissue of a living being 1 2002
7,419,482 Systems and methods for delivering agents into targeted tissue of a living being 2 2004
 
STRYKER NV OPERATIONS LIMITED (3)
6,623,452 Drug delivery catheter having a highly compliant balloon with infusion holes 61 2000
7,758,541 Targeted drug delivery device and method 26 2004
8,206,346 Targeted drug delivery device and method 0 2010
 
VEGENICS PTY LIMITED (3)
6,958,147 Use of VEGF-C to prevent restenosis 11 1999
8,455,453 Use of VEGF-D gene to prevent restenosis 0 2005
8,278,098 Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins 0 2011
 
ABBOTT LABORATORIES (2)
8,236,039 Vena cava filter having wall contacts 1 2008
8,292,913 Method of reducing rigidity of angioplasty balloon sections 0 2011
 
AMS RESEARCH CORPORATION (2)
8,262,605 Needleless delivery systems 0 2005
8,808,232 Needleless delivery systems 0 2012
 
APPLIED MEDICAL TECHNOLOGY, INC. (2)
8,047,986 Molded and undivided medical penetrating device 0 2007
8,382,664 Molded and undivided medical penetrating device 0 2011
 
BOSTON SCIENTIFIC CORPORATION (2)
6,494,861 Drug delivery system 10 1997
5,868,719 Drug delivery balloon catheter device 62 1997
 
Caliber Therapeutics, Inc. (2)
8,696,644 Balloon catheter systems for delivery of dry drug delivery vesicles to a vessel in the body 0 2010
8,715,230 Balloon catheter systems for delivery of dry drug delivery vesicles to a vessel in the body 0 2013
 
Cardeon Corporation (2)
6,267,747 Aortic catheter with porous aortic root balloon and methods for inducing cardioplegic arrest 33 1999
6,835,188 Aortic catheter with porous aortic root balloon and methods for inducing cardioplegic arrest 5 2001
 
DynamOx, Inc. (2)
7,008,535 Apparatus for oxygenating wastewater 24 2000
7,294,278 Method for oxygenating wastewater 7 2005
 
Endoluminal Therapeutics, Inc. (2)
5,914,345 Treatment of tissues to reduce subsequent response to injury 24 1994
6,071,956 Treatment of tissues to reduce subsequent response to injury 22 1998
 
ETHICON, INC. (2)
6,808,518 Methods and devices for treating diseased blood vessels 21 2001
7,611,484 Methods and devices for treating diseased blood vessels 9 2004
 
GORE ENTERPRISE HOLDINGS, INC. (2)
7,279,208 Thin-wall polytetrafluoroethylene tube 18 2000
8,003,180 Thin-wall polytetrafluoroethylene tube 1 2007
 
JPMORGAN CHASE BANK, N.A. (2)
6,716,252 Prostatic stent with localized tissue engaging anchoring means and methods for inhibiting obstruction of the prostatic urethra 21 2001
6,682,555 Methods for treating the prostate and inhibiting obstruction of the prostatic urethra using biodegradable stents 23 2001
 
KIMBERLY-CLARK WORLDWIDE, INC. (2)
7,465,291 Method of fluid delivery and catheters for use with same 10 2003
7,959,623 Method of fluid delivery and catheters for use with same 2 2008
 
MICRO THERAPEUTICS, INC. (2)
5,795,331 Balloon catheter for occluding aneurysms of branch vessels 107 1994
6,635,027 Method and apparatus for intramural delivery of a substance 34 2000
 
SYNTHES USA, LLC (2)
6,632,235 Inflatable device and method for reducing fractures in bone and in treating the spine 154 2001
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THEROX, INC. (2)
6,235,007 Atraumatic fluid delivery devices 55 1998
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Vascular Insights LLC (2)
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VEIN RX, INC. (2)
7,077,836 Methods and apparatus for sclerosing the wall of a varicose vein 10 2001
8,157,747 Single-use indicator for a surgical instrument and a surgical instrument incorporating same 0 2008
 
XRT CORP. (2)
5,713,853 Methods for treating thrombosis 133 1995
6,799,075 X-ray catheter 34 1996
 
YALE UNIVERSITY (2)
7,862,575 Vascular ablation apparatus and method 7 2003
8,465,508 Vascular ablation apparatus and method 0 2007
 
ABACUS DESIGN & DEVELOPMENT, INC. (1)
5,653,689 Infusion catheter 80 1995
 
ABBOTT LABORATORIES VASCULAR ENTERPRISES LIMITED (1)
8,591,565 Process for loading a stent onto a stent delivery system 0 2009
 
ADGERO BIOPHARMACEUTICALS, INC. (1)
7,396,354 Light delivery catheter 3 2003
 
ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (1)
5,306,250 Method and apparatus for intravascular drug delivery 186 1992
 
Angio Dynamics (1)
7,914,503 Method and apparatus for selective material delivery via an intra-renal catheter 1 2005
 
BARD CONNAUGHT (1)
6,048,332 Dimpled porous infusion balloon 81 1998
 
BAYER MEDICAL CARE INC. (1)
8,876,754 Catheter with filtering and sensing elements 0 2006
 
BOSTON SCIENTIFIC LIMITED (1)
6,306,166 Loading and release of water-insoluble drugs 154 1998
 
BRAINLAB AG (1)
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BY-PASS INC. (1)
8,439,890 Material delivery system 0 2011
 
Cardiac Pacemakers, Inc. (1)
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CARDIO VASCULAR DYNAMICS (1)
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CARDIOCOMMAND, INC. (1)
6,148,222 Esophageal catheters and method of use 101 1998
 
COOK MEDICAL TECHNOLOGIES LLC (1)
8,469,943 Coated implantable medical device 0 2010
 
COVIDIEN LP (1)
6,936,025 Thrombolysis device 34 2000
 
DEKA PRODUCTS LIMITED PARTNERSHIP (1)
6,168,609 Catamenial collector and methods of use 6 1998
 
DURECT CORPORATION (1)
7,438,701 Local concentration management system 5 2001
 
ENDOVASCULAR TECHNOLOGIES, INC. (1)
6,702,802 Catheters with improved transition 35 2000
 
ERBE ELEKTROMEDIZIN GMBH (1)
6,752,799 Method and device for endoscopic injection of at least one fluid 0 1999
 
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6,095,966 X-ray device having a dilation structure for delivering localized radiation to an interior of a body 83 1998
 
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HEMOTEQ AG (1)
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INTERVENTIONAL INNOVATION CORPORATION (1)
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JAGOTEC AG (1)
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JOMED GMBH (1)
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LARY RESEARCH & DEVELOPMENT, LLC (1)
7,985,200 Apparatus for delivering an intravascular drug 1 2006
 
Loyola University of Chicago (1)
5,599,307 Catheter and method for the prevention and/or treatment of stenotic processes of vessels and cavities 143 1995
 
MATRIGEN, INC. (1)
5,833,658 Catheters for the delivery of solutions and suspensions 56 1996
 
MEDTRONIC VASCULAR, INC. (1)
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NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (1)
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NEOMEND, INC. (1)
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OLYMPUS OPTICAL CO., LTD. (1)
5,702,384 Apparatus for gene therapy 53 1995
 
PINPOINT THERAPEUTICS, INC. (1)
6,699,231 Methods and apparatus for perfusion of isolated tissue structure 76 1998
 
Radiance Medical Systems, Inc. (1)
6,027,487 Low profile infusion catheter 8 1996
 
SCHNEIDER (USA) INC. (1)
5,772,632 Dilation-drug delivery catheter 43 1997
 
SciMed (1)
5,554,119 Drug delivery catheter with manifold 199 1994
 
SHERWOOD SERVICES AG (1)
5,269,755 Catheter with outer membrane medicament delivery system 90 1992
 
Surgical Systems & Instruments, Inc. (1)
5,306,244 Method of guidewire insertion 53 1991
 
TERUMO KABUSHIKI KAISHA (1)
5,547,472 Catheter with medicament injection pores 43 1995
 
VASCULAR BIOGENICS LTD. (1)
8,415,318 Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy 4 2011
 
Other [Check patent profile for assignment information] (7)
5,498,251 Tissue perfusion catheter 13 1994
5,674,239 Intravaginal balloon for blood leakage prevention 16 1995
6,053,900 Apparatus and method for delivering diagnostic and therapeutic agents intravascularly 74 1998
7,621,908 Catheter for manipulation of the esophagus 4 2005
8,894,614 Devices, systems and methods useable for treating frontal sinusitis 0 2006
8,328,771 Method for fluid delivery and catheters for use with same 0 2011
8,889,211 Coating process for drug delivery balloons using heat-induced rewrap memory 0 2011