US Patent No: 5,091,171

Number of patents in Portfolio can not be more than 2000

Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use

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ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
FLEET CAPITAL CORPORATIONWILMINGTON, DE479
TRISTRATA TECHNOLOGY, INC.WILMINGTON, DE73

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Van, Scott Eugene J Abington, PA 145 2126
Yu, Ruey J Chalfont, PA 164 2423

Cited Art

Patent Info (Count) # Cites Year
 
UNION CARBIDE CORPORATION (1)
4,929,722 Acid decrystallization of aminopolysaccharides and derivatives thereof 93 1988
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
4,363,815 Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions 186 1980

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
TRISTRATA TECHNOLOGY, INC. (70)
5,385,938 Method of using glycolic acid for treating wrinkles 69 1992
5,665,776 Additives enhancing topical actions of therapeutic agents 30 1993
5,389,677 Method of treating wrinkles using glycalic acid 57 1993
5,702,688 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use 17 1993
5,470,880 Method of using citric acid for the treatment of wrinkles 38 1994
5,422,370 Method of using 2-hydroxypropanoic acid (lactic acid) for the treatment of wrinkles 36 1994
5,547,988 Alleviating signs of dermatological aging with glycolic acid, lactic acid or citric acid 42 1994
5,670,541 Method of treating wrinkles using gulonic acid or gulonolactone 1 1995
5,668,177 Method of treating wrinkles using tartaric acid 1 1995
5,591,774 Method of treating wrinkles using malic acid 3 1995
5,589,505 Method of treating wrinkles using quinic acid or quinolactone 7 1995
5,561,155 Method of treating wrinkles using galacturonic acid or galacturonolactone 1 1995
5,561,159 Method of treating wrinkles using tropic acid 1 1995
5,550,154 Method of treating wrinkles using glucuronic acid or glucuronolactone 1 1995
5,716,992 Method of using mucic acid or mucolactone for treating wrinkles 1 1995
5,677,339 Method of using mandelic acid for treating wrinkles 1 1995
5,677,340 Method of using gluconic acid or gluconolactone for treating wrinkles 3 1995
5,674,899 Method of using lactic acid for treating wrinkles 1 1995
5,674,903 Method of using citric acid for treating wrinkles 1 1995
5,670,542 Method of using glucuronic acid or glucronolactone for treating wrinkles 1 1995
5,670,543 Method of using pantoic acid or pantolactone for treating wrinkles 1 1995
5,656,665 Method of using quinic acid or quinolactone for treating wrinkles 6 1995
5,656,666 Method of using ribonic acid or ribonolactone for treating wrinkles 1 1995
5,654,340 Method of using gulonic acid or gulonolactone for treating wrinkles 2 1995
5,652,267 Method of using saccharic acid or saccharolactone for treating wrinkles 1 1995
5,650,436 Method of using galactonic acid or galactonolactone for treating wrinkles 1 1995
5,650,437 Method of using benzilic acid for treating wrinkles 1 1995
5,650,440 Method of using citramalic acid for treating wrinkles 1 1995
5,648,388 Method of using methyllactic acid for treating wrinkles 1 1995
5,648,391 Method of using galacturonic acid or galacturonolactone for treating wrinkles 1 1995
5,648,395 Method of using tartaric acid for treating wrinkles 2 1995
5,643,952 Method of using 2-phenyllactic acid for treating wrinkles 1 1995
5,643,953 Method of using 3-phenyllactic acid for treating wrinkles 1 1995
5,643,961 Method of using malic acid for treating wrinkles 2 1995
5,643,962 Method of using glucoleptonic acid for treating wrinkles 1 1995
5,643,963 Method of using isocitric acid for treating wrinkles 1 1995
5,637,615 Method of using tropic acid for treating wrinkles 2 1995
5,612,376 Method of treating wrinkles using 3-phenyllactic acid 1 1995
5,599,843 Method of treating wrinkles using 2-phenyllactic acid 1 1995
5,583,156 Method of treating wrinkles using ribonic acid or ribonolactione 2 1995
5,580,902 Method of treating wrinkles using ethyl pyranate 4 1995
5,578,644 Method of treating wrinkles using isocitric acid 1 1995
5,574,067 Method of treating wrinkles using gluconic acid or gluconolactone 1 1995
5,571,841 Method of treating wrinkles using mandelic acid 2 1995
5,565,487 Method of treating wrinkles using galactonic acid or galactonolactone 2 1995
5,561,153 Method of treating wrinkles using mucic acid or mucolactone 1 1995
5,561,156 Method of treating wrinkles using methyllactic acid 1 1995
5,556,882 Methods of treating wrinkles using benzilic acid 1 1995
5,554,651 Method of treating wrinkles using citramalic acid 1 1995
5,550,158 Method of treating wrinkles using glucoheptonic acid 1 1995
5,942,250 Compositions and methods for enhancing the topical effects of sunscreen agents 7 1995
5,834,510 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 2 1995
5,690,967 Compositions for improved topical delivery of lactic acid 7 1995
5,691,378 Method for treating wrinkles using combinations of alpha hydroxyacids and/or alpha ketoacids 3 1995
5,686,489 Alpha hydroxyacid esters for skin aging 9 1995
5,684,044 Methods for improved topical delivery of lactic acid 3 1995
5,681,853 Methods for improved topical delivery of alpha hydroxyacids 5 1995
5,654,336 Methods of using glycolic acid for reversing or retarding the effect of aging on human facial skin 4 1995
5,571,837 Method of treating wrinkles using saccharic acid or saccharolactone 1 1995
5,561,158 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 12 1995
5,889,054 Method of using beta hydroxy acids for treating wrinkles 18 1997
5,962,526 Pharmaceutical compositions containing hydroxycarboxylic acids and/or ketocarboxylic acids and methods of using same 1 1997
5,856,357 Method for treating wrinkles using certain alpha hydroxyacids 4 1997
5,886,042 Amphoteric compostion and polymeric forms of alpha hydroxyacids, and their therapeutic use 21 1997
5,883,128 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use 6 1997
6,060,512 Method of using hydroxycarboxylic acids or related compounds for treating skin changes asociated with intrinsic and extrinsic aging 3 1998
6,051,609 Additives enhancing the effect of therapeutic agents 11 1998
6,384,079 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 8 1999
6,191,167 Pharmaceutical compositions containing hydroxycarboxylic acid and/or ketocarboxylic acids and methods of using the same 10 1999
6,767,924 Method of using hydroxycarboxylic acids or related compounds for treating skin changes associated with intrinsic and extrinsic aging 13 2000
 
L'OREAL (14)
5,824,650 Topical composition containing a substance P antagoinst 30 1995
5,679,360 Substance P antagonist for the treatment of lichens, prurigo, pruritus 9 1995
6,235,291 Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained 4 1996
6,168,809 Alkaline-earth metal salt for the treatment of ocular or palpebral pruritus and dysesthesia 3 1996
5,851,556 Use of a salt of an alkaline-earth metal as TNF-A or substance P inhibitor in a topical composition and composition obtained 19 1996
5,753,211 Nail treatment composition comprising hydroxy carboxylic acid 7 1996
5,858,341 Detergent cosmetic compositions for hair use and use thereof 2 1996
5,858,024 Composition for dyeing keratin fibres containing a substance P antagonist 9 1996
5,900,257 Cosmetic/pharmaceutical compositions comprising lanthanide manganese, tin and/or yttrium salts as substance P antagonists 13 1996
5,866,168 Dermatological/pharmaceutical compositions comprising lanthanide, manganese, tin, zinc, yttrium, cobalt, barium and/or strontium salts as substance P antagonists 11 1996
5,961,996 Nail treatment composition comprising hydroxy carboxylic acid 7 1998
6,051,213 Detergent cosmetic compositions for hair use and use thereof 0 1998
6,333,042 Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained 3 2000
7,537,752 Use of a composition containing an effective quantity of at least one ion chelating agent for increasing the tolerance threshold of a sensitive or intolerant skin 0 2002
 
ALLERGAN, INC. (13)
6,730,308 Tazarotene and alpha hydroxy acid treatment for psoriasis and/or photodamage 2 1999
8,236,023 Apparatus and method for volume adjustment of intragastric balloons 0 2004
8,318,695 Tunably crosslinked polysaccharide compositions 0 2008
8,394,782 Polysaccharide gel formulation having increased longevity 0 2008
8,317,677 Mechanical gastric band with cushions 0 2009
8,394,784 Polysaccharide gel formulation having multi-stage bioactive agent delivery 0 2009
8,338,375 Packaged product 0 2009
8,338,388 Cross-linking of low-molecular weight and high-molecular weight polysaccharides, preparation of injectable monophase hydrogels, polysaccharides and hydrogels obtained 0 2010
8,308,630 Hydraulic gastric band with collapsible reservoir 0 2010
8,382,780 Fatigue-resistant gastric banding device 0 2010
8,377,081 Closure system for tubular organs 0 2010
8,323,180 Hydraulic gastric band with collapsible reservoir 0 2011
8,394,783 Polysaccharide gel formulation having multi-stage bioactive agent delivery 0 2012
 
CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (9)
5,482,710 Cosmetic composition for treatment of pimples and redness 16 1993
5,425,938 Polyamino salts of alpha-hydroxyacids, alpha-ketoacids and related compounds 14 1994
5,690,944 Cosmetic compositions containing lactate dehydrogenase inhibitors 2 1994
5,614,201 Cosmetic composition for treatment of pimples and redness 8 1995
5,552,147 Petroleum jelly with alpha hydroxy carboxylic acids 7 1995
5,595,730 Lactate dehydrogenase inhibitors in cosmetic compositions 3 1996
5,814,662 Skin treatment with alpha-hydroxycarboxylic acids of mixed chain length 11 1996
5,853,742 Cosmetic compositions containing lactate dehydrogenase inhibitors 9 1997
6,036,963 Gluconolactones and glucarolactones as anti-irritants in cosmetic compositions 1 1998
 
ESTEE LAUDER, INC. (7)
5,610,199 Solid lipophilic composition and process for its preparation 23 1994
5,736,537 Dehydroep:androsterone sailcylate useful against skin atrophy 9 1995
5,683,705 Sulfur-based amides and bis-amides useful against skin disorders 2 1996
5,780,517 Solid lipophilic composition and process for its preparation 20 1997
5,948,418 Sulfur-based amides and bis-amides useful against skin disorders 5 1997
6,025,347 Steroid esters useful against skin disorders 6 1998
6,284,750 .alpha.-hydroxyacid esters of DHEA useful against skin disorders 2 2000
 
JR CHEM, LLC (6)
7,927,614 Anti-aging treatment using copper and zinc compositions 0 2006
7,867,522 Method of wound/burn healing using copper-zinc compositions 0 2006
7,687,650 Chemical compositions and methods of making them 1 2006
7,897,800 Chemical compositions and methods of making them 0 2007
8,273,791 Compositions, kits and regimens for the treatment of skin, especially décolletage 0 2008
8,148,563 Chemical compositions and methods of making them 0 2010
 
THE PROCTER & GAMBLE COMPANY (6)
5,652,228 Topical desquamation compositions 17 1995
5,759,524 Photoprotective compositions 16 1996
5,948,416 Stable topical compositions 40 1996
5,849,728 Desquamation compositions 1 1997
H002043 Skin care compositions 0 1997
6,024,942 Photoprotective compositions 21 1997
 
AVON PRODUCTS, INC. (4)
5,932,229 Oxa diacids and related compounds for treating skin conditions 23 1997
6,071,962 Oxa acids and related compounds for treating skin conditions 5 1998
6,534,543 Oxa acids and related compounds for treating skin conditions 1 2001
7,351,745 Compositions and methods of their use for improving the condition and appearance of skin 7 2004
 
BRISTOL-MYERS SQUIBB COMPANY (4)
5,420,106 Method and composition having enhanced alpha-hydroxy acid skin permeation and retention 13 1994
5,705,168 Enhanced permeation of alpha-hydroxy acid enantiomer 2 1995
5,702,711 Method for enhancing the rate of skin permeation of lactic acid through use of the L-enantiomer 2 1995
5,885,596 Methods and compositions for fine lines and/or wrinkles 18 1997
 
UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (4)
6,294,182 Towelette product for minimizing facial fine lines and wrinkles 7 1999
6,287,582 Towelette product 6 2000
6,384,000 Predominantly synthetic bar comprising hydroxy acid salt and specific types and amounts of filler 5 2001
7,176,172 Quaternary ammonium polyol salts as anti-aging actives in personal care compositions 7 2004
 
ELIZABETH ARDEN COMPANY, DIVISION OF CONOPCO, INC. (3)
5,411,734 Non-irritating .alpha.-hydroxy carboxylic acid compositions 9 1993
5,382,432 Cosmetic method for treatment of skin 14 1993
5,472,698 Composition for enhancing lipid production in skin 25 1994
 
GENZYME CORPORATION (3)
5,618,850 Hydroxy-acid cosmetics 25 1995
5,879,688 Hydroxy-acid cosmetics 16 1996
6,261,544 Poly(hydroxy acid)/polymer conjugates for skin applications 19 1999
 
KIMBERLY-CLARK WORLDWIDE, INC. (3)
8,361,553 Methods and compositions for metal nanoparticle treated surfaces 0 2007
8,293,965 Antimicrobial site dressings 0 2007
8,203,029 Silver-containing compositions, devices and methods for making 1 2009
 
MARY KAY INC. (3)
5,520,918 Low irritant skin-cosmetic composition for daily topical use, its application and manufacture 19 1994
5,587,396 Method of ameliorating cellulite by disrupting the barrier function of the stratum corneum 16 1994
5,720,963 Barrier disruption treatments for structurally deteriorated skin 27 1995
 
TRISTRATA, INCORPORATED (3)
RE41339 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use 1 2006
RE41278 N-acetyl aldosamines and related N-acetyl compounds, and their topical use 0 2006
RE42902 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use 0 2009
 
ANDREW JERGENS COMPANY, THE (2)
5,759,557 Skin care composition 3 1996
5,759,558 Skin care composition 7 1997
 
COLETICA (2)
5,869,069 Lipophilic hydroxylated acid, its use in cosmetics and pharmacy, and its process of preparation 1 1996
6,039,961 Lipophilic hydroxylated acid, its use in cosmetics and pharmacy, and its process of preparation 0 1998
 
COSMEDERM TECHNOLOGIES (2)
7,404,967 Topical product formulations containing strontium for reducing skin irritation 1 2001
8,147,855 Methods for inhibiting sensory responses in the skin such as pain and itch using topical product formulations containing strontium 0 2009
 
FD MANAGEMENT, INC. (2)
5,393,526 Cosmetic compositions 14 1994
5,762,947 Cosmetic skin conditioning compositions containing a salicyloxy .alpha.-carboxy acid 3 1997
 
IVO PISCHEL (2)
6,166,249 Creatine pyruvates 6 1997
6,172,111 Creatine pyruvates and a method of producing them 3 1999
 
RAPAPORT, MARC (2)
5,444,091 Method of applying alpha hydroxy acids for treating striae distensae 5 1994
5,760,079 Method of applying alpha hydroxy acids for treating striae distensae 5 1996
 
REVLON CONSUMER PRODUCTS CORPORATION (2)
5,989,533 Hair conditioning compositions containing alpha or beta hydroxy acid esters 17 1997
6,080,390 Moisturizing cosmetic stick compositions 3 1999
 
SHAFFER, BURT (2)
5,505,948 Home skin peel composition for producing healthy and attractive skin 10 1993
5,730,991 Home skin peel composition for producing healthy and attractive skin 14 1996
 
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (2)
5,536,751 Pharmaceutical alpha-keto carboxylic acid compositions method of making and use thereof 14 1994
5,714,515 Pharmaceutical alpha-keto carboxylic acid compositions, method of making and use thereof 12 1996
 
TRUSTEES OF THE MARVIN E. KLEIN M.D. CAPITAL MANAGEMENT TRUST DATED JULY 3, 1974 (2)
6,197,317 Composition and method for the treatment of skin 2 1998
6,703,030 Amino fruit acid composition and method for the treatment of skin 1 2001
 
ALLERGAN INDUSTRIE, SAS (1)
8,357,795 Hyaluronic acid-based gels including lidocaine 0 2009
 
AMWAY CORPORATION (1)
6,184,247 Method of increasing cell renewal rate 15 1999
 
AVICENA GROUP, INC. (1)
7,186,754 Use of creatine or creatine compounds for skin preservation 1 2005
 
BAUSCH & LOMB INCORPORATED (1)
5,885,593 Skin care composition including cyclodextrin materials and method for treating skin therewith 15 1996
 
BEAUTICONTROL COSMETICS, INC. (1)
5,407,958 Therapeutic skin composition 21 1993
 
BEIERSDORF, INC. OF BDF PLAZA (1)
5,561,166 Urea/lactate topical compositions for dry skin 2 1993
 
BIOMED RESEARCH & TECHNOLOGIES, INC. (1)
6,149,924 Composition for enhancing lipid production, barrier function, hydrogen peroxide neutralization, and moisturization of the skin 10 1998
 
BUCK, CAROL J. (1)
6,858,215 Compositions and methods for softening, thinning and removing hyperkeratotic tissue 0 2002
 
COLGATE-PALMOLIVE COMPANY (1)
5,834,409 Scalp care products containing anti itching/anti irritant agents 3 1996
 
DORIT ARAD. (1)
6,888,033 Anti-viral compounds 0 1997
 
E-L MANAGEMENT CORP. (1)
5,942,212 Self tanning composition containing DHA and .alpha. hydroxy acids 4 1997
 
EXEGENICS, INC., D/B/A OPKO HEALTH, INC. (1)
6,828,350 Modulators of cysteine protease 0 2000
 
HAWKEYE-JENSEN, INC. (1)
6,448,251 Zwitterionic-fatty acid compounds having anti-inflammatory properties 0 2000
 
HENKEL CONSUMER GOODS INC. (1)
6,566,313 Shampoo and body wash composition and method of use thereof 15 2001
 
HYDRON TECHNOLOGIES, INC. (1)
5,879,684 Skin tightening formulation and method for treating skin 12 1997
 
ICN PHARMACEUTICALS, INC. (1)
5,599,546 Medicinal facial mask 0 1993
 
IOVATE HEALTH SCIENCES, INC. (1)
5,973,199 Hydrosoluble organic salts of creatine 13 1996
 
ISIS PHARMACEUTICALS, INC. (1)
8,039,444 Antisense permeation enhancers 0 2006
 
KAO CORPORATION (1)
7,189,708 Topical composition for skin 0 2002
 
KRAEMER, KARL THEODOR (1)
6,352,686 Antipsoriatic nail polish 2 1998
 
KYOWA HAKKO KOGYO CO., LTD. (1)
6,013,632 Compounds and their combinations for the treatment of influenza infection 13 1998
 
LONGEVITY NETWORK. LTD. (1)
5,441,740 Cosmetic composition containing alpha hydroxyacids, salicyclic acid, and enzyme mixture of bromelain and papain 15 1994
 
MEDI-CELL LABORATORIES, INC. (1)
6,110,966 Triple action complex 5 1999
 
N. V. PERRICONE LLC (1)
6,417,226 Skin whiteners containing hydroxytetronic acid 5 2000
 
NEOSTRATA COMPANY, INC. (1)
6,159,480 Cosmetic makeup composition 6 1997
 
OSMOTICS CORPORATION (1)
5,785,978 Skin care compositions and methods 23 1996
 
PHADIA AB (1)
7,482,010 Non-anaphylactic forms of grass pollen Phl p 6 allergen and their use 0 2002
 
POLYMER SURFACES GROUP, LLC (1)
7,723,387 Self-neutralizing acid peel for dermatologic use 0 2006
 
ROSLIN, MITCHELL STEVEN (1)
8,251,888 Artificial gastric valve 0 2006
 
SC DICOPHAR (1)
7,759,325 Use of lecithin as a medication for the treatment of psoriasis 0 2006
 
SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (1)
5,686,083 Compositions for treating corns and calluses 6 1995
 
TEXTILE RESEARCH INSTITUTE INC. (1)
5,691,380 Stable n-acetylcysteine compositions and methods for treating human skin therewith 15 1995
 
THE ARAB COMPANY FOR DRUG INDUSTRIES AND MEDICAL APPLICANCES (ACDIMA) (1)
5,646,131 Method for solubilizing drugs using cyclodextrins and carboxylic acids 31 1995
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
6,630,516 Methods and compositions for preventing and treating chronological aging in human skin 2 1998
 
TRAVCO PRODUCTS, INC. (1)
6,255,295 Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue 17 1997
 
TRISTRATE, INCORPORATED (1)
5,827,882 Method of using ethyl pyruvate for treating wrinkles 3 1995
 
UPSHER-SMITH LABORATORIES, INC. (1)
8,013,017 Dermatological compositions and methods 0 2009
 
VIVANT PHARMACEUTICALS (1)
6,169,110 Rejuvenating the skin using a combination of vitamin A and alphahydroxy acids 1 1997
 
WELLA AG (1)
5,961,999 Method of skin care using a skin care preparation containing a betaine ester and an .alpha.-hydroxy acid 15 1998
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (23)
5,627,187 5-FU for treating actinic kerotoses 5 1995
5,621,006 Method for treating acne using benzilic acid 9 1995
5,561,157 Method for enhancing the therapeutic effect of a composition comprising hydroquinone and comprising same 18 1995
5,554,597 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 10 1995
5,554,652 Method of treating wrinkles using alpha hydroxyacids, alpha ketoacids and a sunscreen agent 4 1995
5,554,654 Method for enhancing the therapeutic effect of an anti-acne agent 29 1995
5,683,713 Pharmaceutical compositions for topical application 10 1996
5,773,473 Creatine supplement 26 1997
5,877,212 Molecular complex and control-release of alpha hydroxyacids 11 1997
H2043 Skin care compositions 2 1997
6,231,840 Compositions and methods for the topical treatment of nail fungi conditions 12 1998
6,207,694 Pharmaceutical compositions and methods for managing scalp conditions 8 1998
6,114,337 Zwitteronic-fatty acid compounds having anti-inflammatory properties 3 1998
6,271,246 Pharmaceutical compositions for managing scalp conditions 5 1999
6,335,023 Oligosaccharide aldonic acids and their topical use 26 2000
6,517,822 Formulations and methods for straightening hair 2 2000
6,585,742 Wart removal method and device 3 2001
6,740,327 Oligosaccharide aldonic acids and their topical use 7 2001
6,808,716 N-acetylamino acids, related N-acetyl compounds and their topical use 1 2003
7,241,808 Composition for treatment of skin and method for stabilizing the composition 0 2003
6,835,385 Compositions and methods for softening, thinning and removing hyperkeratotic tissue 0 2003
7,452,545 Oligosaccharide aldonic acids and their topical use 0 2004
7,709,014 Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites 0 2006