US Patent No: 5,091,171

Number of patents in Portfolio can not be more than 2000

Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use

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Abstract

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Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
FLEET CAPITAL CORPORATIONWILMINGTON, DE147
TRISTRATA TECHNOLOGY, INC.WILMINGTON, DE26

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Van, Scott Eugene J 3 Hidden La., Abington, PA 19001 149 2658
Yu, Ruey J 4 Lindenwold Ave., Ambler, PA 19002 169 3048

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 4,363,815 Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions 197 1980
 
Union Carbide Corporation (1)
* 4,929,722 Acid decrystallization of aminopolysaccharides and derivatives thereof 94 1988
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (37)
* 5,627,187 5-FU for treating actinic kerotoses 6 1995
* 5,621,006 Method for treating acne using benzilic acid 11 1995
* 5,561,157 Method for enhancing the therapeutic effect of a composition comprising hydroquinone and comprising same 18 1995
* 5,554,597 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 10 1995
* 5,554,652 Method of treating wrinkles using alpha hydroxyacids, alpha ketoacids and a sunscreen agent 4 1995
* 5,554,654 Method for enhancing the therapeutic effect of an anti-acne agent 31 1995
* 5,683,713 Pharmaceutical compositions for topical application 14 1996
* 5,773,473 Creatine supplement 26 1997
* 5,877,212 Molecular complex and control-release of alpha hydroxyacids 12 1997
H2043 Skin care compositions 2 1997
* 6,231,840 Compositions and methods for the topical treatment of nail fungi conditions 22 1998
* 6,114,337 Zwitteronic-fatty acid compounds having anti-inflammatory properties 4 1998
6,335,023 Oligosaccharide aldonic acids and their topical use 36 2000
6,517,822 Formulations and methods for straightening hair 4 2000
* 2001/0014,342 Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained 3 2000
* 2001/0022,978 Cosmetic, pharmaceutical or dermatological composition comprising a histamine antagonist, an interleukin-1 antagonist and/or a TNF-alpha antagonist 2 2001
6,585,742 Wart removal method and device 7 2001
6,740,327 Oligosaccharide aldonic acids and their topical use 12 2001
6,808,716 N-acetylamino acids, related N-acetyl compounds and their topical use 2 2003
* 2004/0176,453 Method of treating time-dependent changes in human subjects 0 2003
* 2004/0033,963 Urea composition 7 2003
7,241,808 Composition for treatment of skin and method for stabilizing the composition 0 2003
6,835,385 Compositions and methods for softening, thinning and removing hyperkeratotic tissue 0 2003
* 2004/0057,974 Antiwrinkle composition and age reversal complex 2 2003
7,452,545 Oligosaccharide aldonic acids and their topical use 0 2004
* 2004/0180,854 Oligosaccharide aldonic acids and their topical use 2 2004
* 2004/0220,259 Topical treatment of dermatological disorders associated with reactive or dilated blood vessels 25 2004
* 2007/0099,982 Use of chp as an inhibitor of glutathione s-transferases and collagen IV 0 2004
* 2006/0200,174 Wart removal method and device 0 2006
* 2007/0004,668 Antisense permeation enhancers 4 2006
7,709,014 Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites 0 2006
* 2010/0099,632 Oligosaccharide Aldonic Acids and Their Topical Use 0 2009
RE44302 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use 0 2010
* 2010/0292,667 Self-Neutralizing Acid Peel for Dermatologic Use 0 2010
8,992,898 Antiperspirants and deodorants 0 2010
* 2011/0091,403 OLIGOSACCHARIDE ALDONIC ACIDS AND THEIR TOPICAL USE 1 2010
* 2011/0178,318 METHODS OF MAKING BIMETAL COMPLEXES 0 2011
 
E-L MANAGEMENT CORP. (1)
* 5,942,212 Self tanning composition containing DHA and .alpha. hydroxy acids 4 1997
 
UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (12)
6,294,182 Towelette product for minimizing facial fine lines and wrinkles 8 1999
6,287,582 Towelette product 7 2000
6,384,000 Predominantly synthetic bar comprising hydroxy acid salt and specific types and amounts of filler 5 2001
* 2003/0228,337 Personal care compositions with hydroxy amine neutralized polymers 1 2002
* 2003/0224,023 Cosmetic compositions with hydroxy amine salts of malonic acid 9 2003
* 2003/0224,027 Cosmetic compositions with ammonium malonates 9 2003
* 2004/0185,073 Cosmetic compositions containing salts of malonic acid 0 2003
* 2004/0185,015 Sunscreen cosmetic compositions storage stabilized with malonate salts 9 2003
* 2004/0185,074 Odor control in amine salt containing cosmetic compositions 9 2003
* 2004/0202,689 Terpenoid fragrance components stabilized with malonic acid salts 10 2004
7,176,172 Quaternary ammonium polyol salts as anti-aging actives in personal care compositions 12 2004
* 2006/0089,277 Quaternary ammonium polyol salts as anti-aging actives in personal care compositions 4 2004
 
KRAEMER, KARL THEODOR (1)
* 6,352,686 Antipsoriatic nail polish 3 1998
 
The Andrew Jergens Company (2)
* 5,759,557 Skin care composition 6 1996
* 5,759,558 Skin care composition 8 1997
 
CRITICAL THERAPEUTICS, INC. (1)
* 2004/0068,006 Method for preventing acute renal failure 3 2003
 
IVO PISCHEL (2)
* 6,166,249 Creatine pyruvates 8 1997
* 6,172,111 Creatine pyruvates and a method of producing them 6 1999
 
Amway Corporation (1)
* 6,184,247 Method of increasing cell renewal rate 25 1999
 
Longevity Network. Ltd. (1)
* 5,441,740 Cosmetic composition containing alpha hydroxyacids, salicyclic acid, and enzyme mixture of bromelain and papain 16 1994
 
SHAFFER, BURT (2)
* 5,505,948 Home skin peel composition for producing healthy and attractive skin 12 1993
* 5,730,991 Home skin peel composition for producing healthy and attractive skin 14 1996
 
COLGATE-PALMOLIVE COMPANY (1)
* 5,834,409 Scalp care products containing anti itching/anti irritant agents 28 1996
 
APOLLO ENDOSURGERY, INC. (33)
8,236,023 Apparatus and method for volume adjustment of intragastric balloons 5 2004
* 2007/0173,881 Apparatus and method for volume adjustment of intragastric balloons 53 2004
8,900,117 Releasably-securable one-piece adjustable gastric band 0 2005
8,317,677 Mechanical gastric band with cushions 4 2009
* 2010/0087,843 Mechanical Gastric Band With Cushions 66 2009
8,758,221 Source reservoir with potential energy for remotely adjustable gastric banding system 0 2010
* 2011/0208,229 SOURCE RESERVOIR WITH POTENTIAL ENERGY FOR REMOTELY ADJUSTABLE GASTRIC BANDING SYSTEM 0 2010
8,840,541 Pressure sensing gastric banding system 0 2010
* 2011/0208,220 PRESSURE SENSING GASTRIC BANDING SYSTEM 0 2010
9,028,394 Self-adjusting mechanical gastric band 0 2010
* 2010/0280,310 Laparoscopic Gastric Band With Active Agents 32 2010
8,517,915 Remotely adjustable gastric banding system 0 2010
* 2010/0305,397 HYDRAULIC-MECHANICAL GASTRIC BAND 32 2010
8,308,630 Hydraulic gastric band with collapsible reservoir 3 2010
* 2010/0324,358 HYDRAULIC GASTRIC BAND WITH COLLAPSIBLE RESERVOIR 36 2010
8,382,780 Fatigue-resistant gastric banding device 0 2010
* 2010/0324,359 FATIGUE-RESISTANT GASTRIC BANDING DEVICE 31 2010
* 2011/0054,248 GASTRIC BAND WITH ELECTRIC STIMULATION 1 2010
8,377,081 Closure system for tubular organs 0 2010
* 2011/0040,141 CLOSURE SYSTEM FOR TUBULAR ORGANS 1 2010
8,961,393 Gastric band devices and drive systems 0 2010
* 2011/0184,229 LAPAROSCOPIC GASTRIC BAND WITH ACTIVE AGENTS 3 2011
* 2011/0152,608 FLOW CONTROL METHOD AND DEVICE 1 2011
8,845,513 Remotely adjustable gastric banding device 0 2011
8,323,180 Hydraulic gastric band with collapsible reservoir 2 2011
8,905,915 Self-regulating gastric band with pressure data processing 0 2011
9,044,298 Self-adjusting gastric band 0 2011
8,876,694 Tube connector with a guiding tip 0 2011
8,961,394 Self-sealing fluid joint for use with a gastric band 0 2011
8,900,118 Dome and screw valves for remotely adjustable gastric banding systems 0 2013
9,050,165 Remotely adjustable gastric banding system 0 2013
9,295,573 Self-adjusting gastric band having various compliant components and/or a satiety booster 0 2013
9,192,501 Remotely powered remotely adjustable gastric band system 0 2013
 
COLETICA (1)
* 6,039,961 Lipophilic hydroxylated acid, its use in cosmetics and pharmacy, and its process of preparation 0 1998
 
BEIERSDORF AG (6)
* 2004/0241,197 Cosmetic or dermatological preparations including creatinine or a derivative thereof and creatine or a derivative thereof and methods of applying the preparations to the skin 4 2004
* 2005/0142,154 Cosmetic preparations containing creatine and/or creatinine and organic thickeners 5 2004
* 2005/0137,260 Active substance combination of creatine and/or creatinine and phenoxyethanol 0 2004
* 8,808,670 Cosmetic and dermatological photoprotective formulations 0 2005
* 2006/0008,426 Cosmetic and dermatological photoprotective formulations 11 2005
* 2006/0018,869 Cosmetic or dermatological preparation with a content of creatine, creatinine or derivatives thereof in combination with soybean germ extract 11 2005
 
ZARS PHARMA, INC. (1)
* 2008/0019,927 Compositions and methods for dermally treating neuropathy with minoxidil 9 2007
 
ROSLIN, MITCHELL STEVEN (2)
8,251,888 Artificial gastric valve 2 2006
* 2006/0235,448 Artificial gastric valve 94 2006
 
ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (3)
* 5,411,734 Non-irritating .alpha.-hydroxy carboxylic acid compositions 11 1993
* 5,382,432 Cosmetic method for treatment of skin 14 1993
* 5,472,698 Composition for enhancing lipid production in skin 31 1994
 
FD MANAGEMENT, INC. (2)
* 5,393,526 Cosmetic compositions 15 1994
* 5,762,947 Cosmetic skin conditioning compositions containing a salicyloxy .alpha.-carboxy acid 5 1997
 
The Regents of the University of California (1)
* 2013/0209,360 Compositions and Methods for Imaging 0 2011
 
Roslin, Mitchell (1)
8,623,042 Artificial gastric valve 0 2010
 
L'OREAL (23)
* 5,824,650 Topical composition containing a substance P antagoinst 68 1995
* 5,679,360 Substance P antagonist for the treatment of lichens, prurigo, pruritus 12 1995
6,235,291 Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained 5 1996
6,168,809 Alkaline-earth metal salt for the treatment of ocular or palpebral pruritus and dysesthesia 12 1996
* 5,851,556 Use of a salt of an alkaline-earth metal as TNF-A or substance P inhibitor in a topical composition and composition obtained 35 1996
* 5,753,211 Nail treatment composition comprising hydroxy carboxylic acid 10 1996
* 5,858,341 Detergent cosmetic compositions for hair use and use thereof 2 1996
* 5,858,024 Composition for dyeing keratin fibres containing a substance P antagonist 18 1996
* 5,900,257 Cosmetic/pharmaceutical compositions comprising lanthanide manganese, tin and/or yttrium salts as substance P antagonists 17 1996
* 5,866,168 Dermatological/pharmaceutical compositions comprising lanthanide, manganese, tin, zinc, yttrium, cobalt, barium and/or strontium salts as substance P antagonists 17 1996
* 5,961,996 Nail treatment composition comprising hydroxy carboxylic acid 11 1998
* 6,051,213 Detergent cosmetic compositions for hair use and use thereof 0 1998
6,333,042 Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained 3 2000
7,537,752 Use of a composition containing an effective quantity of at least one ion chelating agent for increasing the tolerance threshold of a sensitive or intolerant skin 0 2002
* 2003/0039,669 Use of a composition containing an effective quantity of at least one chelating agent for partially or totally reducing the symptoms associated with histamine release in the organism 0 2002
* 2003/0026,820 Use of a compositon containing an effective quantity of at least one ion chelating agent for increasing the tolerance threshold of a sensitive or intolerant skin 8 2002
* 2003/0003,123 Compositions and regime/regimen for treating the adverse signs of cutaneous skin aging 0 2002
* 8,492,366 Enhancedly-solubilized beta-hydroxy acids and higher potency skin peels formulated therefrom 0 2003
* 2006/0280,711 Process for treating marionette lines 1 2005
* 2007/0225,360 Anti-aging composition containing phloretin 4 2007
* 2010/0228,181 USE OF GREEN LIGHT TO ACTIVATE L-AMINO ACID OXIDASE 0 2008
9,248,082 Anti-aging composition containing phloretin 0 2009
* 2009/0286,874 Anti-aging composition containing phloretin 1 2009
 
BeautiControl Cosmetics, Inc. (1)
* 5,407,958 Therapeutic skin composition 25 1993
 
BRISTOL-MYERS SQUIBB COMPANY (4)
* 5,420,106 Method and composition having enhanced alpha-hydroxy acid skin permeation and retention 13 1994
* 5,705,168 Enhanced permeation of alpha-hydroxy acid enantiomer 3 1995
* 5,702,711 Method for enhancing the rate of skin permeation of lactic acid through use of the L-enantiomer 6 1995
* 5,885,596 Methods and compositions for fine lines and/or wrinkles 18 1997
 
GENZYME CORPORATION (3)
* 5,618,850 Hydroxy-acid cosmetics 32 1995
* 5,879,688 Hydroxy-acid cosmetics 25 1996
6,261,544 Poly(hydroxy acid)/polymer conjugates for skin applications 51 1999
 
ALLERGAN INDUSTRIE, SAS (20)
8,450,475 Hyaluronic acid-based gels including lidocaine 3 2009
8,357,795 Hyaluronic acid-based gels including lidocaine 30 2009
* 2010/0028,438 Hyaluronic Acid-Based Gels Including Lidocaine 1 2009
* 2011/0172,180 HEAT STABLE HYALURONIC ACID COMPOSITIONS FOR DERMATOLOGICAL USE 26 2010
8,586,562 Fluid compositions for improving skin conditions 10 2010
* 2011/0224,164 FLUID COMPOSITIONS FOR IMPROVING SKIN CONDITIONS 17 2010
* 2011/0118,206 HYALURONIC ACID BASED FORMULATIONS 28 2010
* 2011/0171,311 STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES 27 2011
9,114,188 Stable hydrogel compositions including additives 0 2012
8,822,676 Hyaluronic acid-based gels including lidocaine 1 2012
8,946,192 Heat stable hyaluronic acid compositions for dermatological use 3 2012
8,563,532 Cross-linking of low-molecular weight and high-molecular weight polysaccharides, preparation of injectable monophase hydrogels, polysaccharides and hydrogels obtained 10 2012
9,089,517 Hyaluronic acid-based gels including lidocaine 0 2012
9,089,518 Hyaluronic acid-based gels including lidocaine 1 2012
9,238,013 Hyaluronic acid-based gels including lidocaine 0 2013
9,358,322 Hyaluronic acid-based gels including lidocaine 0 2013
9,062,130 Cross-linking of low-molecular weight and high-molecular weight polysaccharides, preparation of injectable monophase hydrogels, polysaccharides and hydrogels obtained 0 2013
9,125,840 Methods for improving skin conditions 0 2013
8,921,338 Fluid compositions for improving skin conditions 0 2013
9,089,519 Hyaluronic acid-based gels including lidocaine 0 2014
 
Medi-Cell Laboratories, Inc. (1)
* 6,110,966 Triple action complex 36 1999
 
The Procter & Gamble Company (7)
* 5,652,228 Topical desquamation compositions 37 1995
* 5,759,524 Photoprotective compositions 17 1996
* 5,948,416 Stable topical compositions 72 1996
* 5,849,728 Desquamation compositions 1 1997
H002043 Skin care compositions 0 1997
* 6,024,942 Photoprotective compositions 56 1997
* 2004/0176,273 Regulation of mammalian keratinous tissue using hexamidine compositions 7 2004
 
ALLERGAN INDUSTRIE, SAS, A FRENCH SOCIETE PAR ACTIONS SIMPLIFIEE (SIMPLIFIED JOINTSTOCK COMPANY) (2)
* 2011/0171,286 HYALURONIC ACID COMPOSITIONS FOR DERMATOLOGICAL USE 32 2010
9,333,160 Heat stable hyaluronic acid compositions for dermatological use 0 2012
 
SHISEIDO COMPANY, LTD. (2)
* 2011/0065,794 Wrinkle-preventing and improving composition 0 2010
* 2012/0157,388 EXTERNAL COMPOSITION FOR SKIN 0 2012
 
MURAD, INC. (1)
6,271,246 Pharmaceutical compositions for managing scalp conditions 8 1999
 
Buck, Carol J. (1)
6,858,215 Compositions and methods for softening, thinning and removing hyperkeratotic tissue 1 2002
 
TEXTILE RESEARCH INSTITUTE (1)
* 5,691,380 Stable n-acetylcysteine compositions and methods for treating human skin therewith 27 1995
 
STIEFEL LABORATORIES, INC. (1)
* 2006/0269,495 Alpha hydroxy acid compositions 3 2005
 
ALLERGAN, INC. (33)
* 6,730,308 Tazarotene and alpha hydroxy acid treatment for psoriasis and/or photodamage 8 1999
* 2008/0293,637 Cross-linked collagen and uses thereof 35 2008
8,318,695 Tunably crosslinked polysaccharide compositions 28 2008
* 2009/0036,403 Tunably Crosslinked Polysaccharide Compositions 42 2008
8,697,044 Crossed-linked hyaluronic acid and collagen and uses thereof 0 2008
* 2009/0093,755 CROSSED-LINKED HYALURONIC ACID AND COLLAGEN AND USES THEREOF 42 2008
8,394,782 Polysaccharide gel formulation having increased longevity 14 2008
* 2009/0143,331 POLYSACCHARIDE GEL FORMULATION HAVING INCREASED LONGEVITY 38 2008
* 2009/0143,348 POLYSACCHARIDE GEL COMPOSITIONS AND METHODS FOR SUSTAINED DELIVERY OF DRUGS 40 2008
8,513,216 Polysaccharide gel formulation having increased longevity 11 2009
* 2010/0004,198 POLYSACCHARIDE GEL FORMULATION HAVING INCREASED LONGEVITY 37 2009
8,394,784 Polysaccharide gel formulation having multi-stage bioactive agent delivery 18 2009
* 2010/0098,764 POLYSACCHARIDE GEL FORMULATION HAVING MULTI-STAGE BIOACTIVE AGENT DELIVERY 37 2009
8,338,375 Packaged product 32 2009
* 2010/0099,623 Cross-Linked Collagen and Uses Thereof 40 2009
* 2010/0099,624 CROSS-LINKED COLLAGEN AND USES THEREOF 7 2009
* 2010/0185,049 DOME AND SCREW VALVES FOR REMOTELY ADJUSTABLE GASTRIC BANDING SYSTEMS 36 2010
8,338,388 Cross-linking of low-molecular weight and high-molecular weight polysaccharides, preparation of injectable monophase hydrogels, polysaccharides and hydrogels obtained 28 2010
* 2011/0077,737 Tunably Crosslinked Polysaccharide Compositions 32 2010
* 2011/0137,112 GASTRIC BAND WITH ELECTRIC STIMULATION 4 2010
8,691,279 Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation 3 2011
9,005,605 Compositions and soft tissue replacement methods 1 2012
8,889,123 Compositions and soft tissue replacement methods 0 2012
8,883,139 Compositions and soft tissue replacement methods 0 2012
8,697,057 Compositions and soft tissue replacement methods 1 2012
8,703,118 Crossed-linked hyaluronic acid and collagen and uses thereof 0 2012
8,394,783 Polysaccharide gel formulation having multi-stage bioactive agent delivery 15 2012
9,149,422 Dermal filler compositions including antioxidants 0 2012
9,393,263 Dermal filler compositions including antioxidants 0 2012
9,408,797 Dermal filler compositions for fine line treatment 0 2012
8,853,184 Polysaccharide gel formulation having increased longevity 3 2013
9,265,761 Compositions and methods for treating purpura 0 2014
9,012,517 Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation 1 2014
 
UNILEVER N.V. (1)
* 6,207,694 Pharmaceutical compositions and methods for managing scalp conditions 22 1998
 
Vivant Pharmaceuticals (1)
6,169,110 Rejuvenating the skin using a combination of vitamin A and alphahydroxy acids 1 1997
 
ALLERGAN HOLDINGS FRANCE S.A.S. (1)
9,228,027 Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof 0 2009
 
ZARS, INC. (3)
* 2007/0196,293 Compositions and methods for treating photo damaged skin 12 2006
* 2007/0196,452 Flux-enabling compositions and methods for dermal delivery of drugs 17 2006
* 2007/0189,978 Compositions and methods for dermally treating musculoskeletal pain 22 2006
 
WELLA AG (1)
* 5,961,999 Method of skin care using a skin care preparation containing a betaine ester and an .alpha.-hydroxy acid 17 1998
 
ISIS PHARMACEUTICALS, INC. (2)
* 2003/0176,379 Antisense permeation enhancers 4 2002
8,039,444 Antisense permeation enhancers 0 2006
 
Chesebrough-Pond's USA Co., Division of Conopco, Inc. (9)
* 5,482,710 Cosmetic composition for treatment of pimples and redness 18 1993
* 5,425,938 Polyamino salts of alpha-hydroxyacids, alpha-ketoacids and related compounds 14 1994
* 5,690,944 Cosmetic compositions containing lactate dehydrogenase inhibitors 2 1994
* 5,614,201 Cosmetic composition for treatment of pimples and redness 8 1995
* 5,552,147 Petroleum jelly with alpha hydroxy carboxylic acids 14 1995
* 5,595,730 Lactate dehydrogenase inhibitors in cosmetic compositions 3 1996
* 5,814,662 Skin treatment with alpha-hydroxycarboxylic acids of mixed chain length 11 1996
* 5,853,742 Cosmetic compositions containing lactate dehydrogenase inhibitors 16 1997
* 6,036,963 Gluconolactones and glucarolactones as anti-irritants in cosmetic compositions 1 1998
 
NUVO RESEARCH INC. (10)
8,907,153 Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same 0 2005
* 2005/0276,842 Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same 67 2005
8,741,332 Compositions and methods for dermally treating neuropathic pain 0 2006
8,741,333 Compositions and methods for treating dermatitis or psoriasis 0 2006
* 2007/0196,325 Compositions and methods for dermally treating infections 15 2006
* 2007/0196,458 Compositions and methods for dermally treating neuropathic pain 10 2006
* 2007/0196,457 Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs 22 2006
* 2007/0190,124 Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs 26 2006
* 2007/0280,972 Adhesive solid gel-forming formulations for dermal drug delivery 21 2007
* 2010/0267,678 FLUX-ENABLING COMPOSITIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS 8 2010
 
HENKEL CONSUMER GOODS INC. (1)
6,566,313 Shampoo and body wash composition and method of use thereof 17 2001
 
TRUSTEES OF THE MARVIN E. KLEIN M.D. CAPITAL MANAGEMENT TRUST DATED JULY 3, 1974 (2)
6,197,317 Composition and method for the treatment of skin 4 1998
6,703,030 Amino fruit acid composition and method for the treatment of skin 1 2001
 
Estee Lauder Inc. (7)
* 5,610,199 Solid lipophilic composition and process for its preparation 26 1994
* 5,736,537 Dehydroep:androsterone sailcylate useful against skin atrophy 11 1995
* 5,683,705 Sulfur-based amides and bis-amides useful against skin disorders 2 1996
* 5,780,517 Solid lipophilic composition and process for its preparation 21 1997
* 5,948,418 Sulfur-based amides and bis-amides useful against skin disorders 5 1997
* 6,025,347 Steroid esters useful against skin disorders 6 1998
6,284,750 .alpha.-hydroxyacid esters of DHEA useful against skin disorders 2 2000
 
BEIERSDORF, INC. OF BDF PLAZA (1)
* 5,561,166 Urea/lactate topical compositions for dry skin 2 1993
 
TRISTRATE, INCORPORATED (1)
* 5,827,882 Method of using ethyl pyruvate for treating wrinkles 3 1995
 
SC Dicophar (2)
* 7,759,325 Use of lecithin as a medication for the treatment of psoriasis 1 2006
* 2008/0153,782 Use of Lecithin as a Medication for the Treatment of Psoriasis 0 2006
 
ELC MANAGEMENT LLC (1)
* 2009/0285,866 Self-healing polymer compositions 2 2008
 
MARY KAY INC. (4)
* 5,520,918 Low irritant skin-cosmetic composition for daily topical use, its application and manufacture 58 1994
* 5,587,396 Method of ameliorating cellulite by disrupting the barrier function of the stratum corneum 16 1994
* 5,720,963 Barrier disruption treatments for structurally deteriorated skin 34 1995
* 2010/0260,695 COMBINATION OF PLANT EXTRACTS TO IMPROVE SKIN TONE 4 2009
 
WORLDWIDE BEAUTY HOLDINGS, LLC (2)
7,723,387 Self-neutralizing acid peel for dermatologic use 0 2006
* 2008/0003,246 Self-Neutralizing Acid Peel for Dermatologic Use 1 2006
 
The Arab Company For Drug Industries And Medical Applicances (ACDIMA) (1)
* 5,646,131 Method for solubilizing drugs using cyclodextrins and carboxylic acids 33 1995
 
BEIERSDORF AF, (1)
* 2005/0131,065 Active substance combination of creatine and/or creatinine and a retinoid 0 2004
 
TRAVCO PRODUCTS, INC. (1)
6,255,295 Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue 22 1997
 
ICN PHARMACEUTICALS, INC. (1)
* 5,599,546 Medicinal facial mask 1 1993
 
SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (1)
* 5,686,083 Compositions for treating corns and calluses 9 1995
 
AVENT, INC. (14)
8,679,523 Oxygen-delivery closed cell foam matrix for wound treatment 1 2000
* 2001/0041,188 Methods and compositions for improved delivery devices 14 2000
8,486,426 Methods and compositions for treatment of dermal conditions 0 2003
* 2004/0096,410 Methods and compositions for treatment of dermal conditions 21 2003
8,900,624 Antimicrobial silver compositions 0 2005
* 2009/0035,342 Antimicrobial Devices and Compositions 30 2005
* 2007/0003,603 Antimicrobial silver compositions 65 2005
9,289,378 Antimicrobial amorphous compositions 0 2005
* 2007/0254,044 Antimicrobial Amorphous Compositions 29 2005
8,361,553 Methods and compositions for metal nanoparticle treated surfaces 4 2007
8,293,965 Antimicrobial site dressings 1 2007
* 2007/0293,800 Antimicrobial site dressings 29 2007
8,203,029 Silver-containing compositions, devices and methods for making 4 2009
* 2010/0190,004 ANTIMICROBIAL LAMINATE CONSTRUCTS 2 2009
 
PHADIA AB (1)
* 7,482,010 Non-anaphylactic forms of grass pollen Phl p 6 allergen and their use 0 2002
 
Biomed Research & Technologies, Inc. (3)
* 6,149,924 Composition for enhancing lipid production, barrier function, hydrogen peroxide neutralization, and moisturization of the skin 15 1998
9,421,262 Compositions and methods for treating dermatological conditions 0 2009
* 2011/0098,229 COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL CONDITIONS 0 2009
 
The United States of America as represented by the Secretary of the Army (2)
* 5,536,751 Pharmaceutical alpha-keto carboxylic acid compositions method of making and use thereof 14 1994
* 5,714,515 Pharmaceutical alpha-keto carboxylic acid compositions, method of making and use thereof 15 1996
 
UPSHER-SMITH LABORATORIES, INC. (2)
* 2003/0017,181 Dermatological compositions and methods 7 2002
8,013,017 Dermatological compositions and methods 0 2009
 
Osmotics Corporation (1)
* 5,785,978 Skin care compositions and methods 24 1996
 
WILLIAM MARSH RICE UNIVERSITY (1)
* 2010/0289,524 Method for Fabrication of a Semiconductor Element and Structure Thereof 1 2010
 
LIBRARY PHARMA, INC. (2)
* 7,186,754 Use of creatine or creatine compounds for skin preservation 3 2005
* 2005/0227,996 Use of creatine or creatine compounds for skin preservation 1 2005
 
N. V. PERRICONE LLC (1)
* 6,417,226 Skin whiteners containing hydroxytetronic acid 5 2000
 
Almirall Hermal GmbH (1)
8,569,320 Topical composition for the treatment of actinic keratosis 0 2009
 
RAPAPORT, MARC (2)
* 5,444,091 Method of applying alpha hydroxy acids for treating striae distensae 6 1994
* 5,760,079 Method of applying alpha hydroxy acids for treating striae distensae 6 1996
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
* 6,630,516 Methods and compositions for preventing and treating chronological aging in human skin 7 1998
 
JR CHEM, LLC (2)
* 2011/0008,271 ROSACEA TREATMENTS USING POLYMETAL COMPLEXES 1 2010
8,952,057 Compositions for anorectal use and methods for treating anorectal disorders 0 2011
 
AVON PRODUCTS, INC. (5)
* 5,932,229 Oxa diacids and related compounds for treating skin conditions 30 1997
* 6,071,962 Oxa acids and related compounds for treating skin conditions 6 1998
6,534,543 Oxa acids and related compounds for treating skin conditions 1 2001
* 7,351,745 Compositions and methods of their use for improving the condition and appearance of skin 13 2004
* 2006/0134,155 Compositions and methods of their use for improving the condition and appearance of skin 3 2004
 
Tristrata Technology, Inc. (70)
5,385,938 Method of using glycolic acid for treating wrinkles 76 1992
* 5,665,776 Additives enhancing topical actions of therapeutic agents 40 1993
* 5,389,677 Method of treating wrinkles using glycalic acid 58 1993
* 5,702,688 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use 17 1993
* 5,470,880 Method of using citric acid for the treatment of wrinkles 40 1994
* 5,422,370 Method of using 2-hydroxypropanoic acid (lactic acid) for the treatment of wrinkles 39 1994
5,547,988 Alleviating signs of dermatological aging with glycolic acid, lactic acid or citric acid 50 1994
* 5,670,541 Method of treating wrinkles using gulonic acid or gulonolactone 1 1995
* 5,668,177 Method of treating wrinkles using tartaric acid 1 1995
* 5,591,774 Method of treating wrinkles using malic acid 3 1995
* 5,589,505 Method of treating wrinkles using quinic acid or quinolactone 7 1995
* 5,561,155 Method of treating wrinkles using galacturonic acid or galacturonolactone 1 1995
* 5,561,159 Method of treating wrinkles using tropic acid 1 1995
* 5,550,154 Method of treating wrinkles using glucuronic acid or glucuronolactone 1 1995
* 5,716,992 Method of using mucic acid or mucolactone for treating wrinkles 1 1995
* 5,677,339 Method of using mandelic acid for treating wrinkles 2 1995
* 5,677,340 Method of using gluconic acid or gluconolactone for treating wrinkles 3 1995
* 5,674,899 Method of using lactic acid for treating wrinkles 1 1995
* 5,674,903 Method of using citric acid for treating wrinkles 1 1995
* 5,670,542 Method of using glucuronic acid or glucronolactone for treating wrinkles 1 1995
* 5,670,543 Method of using pantoic acid or pantolactone for treating wrinkles 1 1995
* 5,656,665 Method of using quinic acid or quinolactone for treating wrinkles 6 1995
* 5,656,666 Method of using ribonic acid or ribonolactone for treating wrinkles 1 1995
* 5,654,340 Method of using gulonic acid or gulonolactone for treating wrinkles 2 1995
* 5,652,267 Method of using saccharic acid or saccharolactone for treating wrinkles 1 1995
* 5,650,436 Method of using galactonic acid or galactonolactone for treating wrinkles 1 1995
* 5,650,437 Method of using benzilic acid for treating wrinkles 1 1995
* 5,650,440 Method of using citramalic acid for treating wrinkles 1 1995
* 5,648,388 Method of using methyllactic acid for treating wrinkles 1 1995
* 5,648,391 Method of using galacturonic acid or galacturonolactone for treating wrinkles 1 1995
* 5,648,395 Method of using tartaric acid for treating wrinkles 2 1995
* 5,643,952 Method of using 2-phenyllactic acid for treating wrinkles 1 1995
* 5,643,953 Method of using 3-phenyllactic acid for treating wrinkles 1 1995
* 5,643,961 Method of using malic acid for treating wrinkles 2 1995
* 5,643,962 Method of using glucoleptonic acid for treating wrinkles 1 1995
* 5,643,963 Method of using isocitric acid for treating wrinkles 1 1995
* 5,637,615 Method of using tropic acid for treating wrinkles 2 1995
* 5,612,376 Method of treating wrinkles using 3-phenyllactic acid 1 1995
* 5,599,843 Method of treating wrinkles using 2-phenyllactic acid 1 1995
* 5,583,156 Method of treating wrinkles using ribonic acid or ribonolactione 2 1995
* 5,580,902 Method of treating wrinkles using ethyl pyranate 4 1995
* 5,578,644 Method of treating wrinkles using isocitric acid 1 1995
* 5,574,067 Method of treating wrinkles using gluconic acid or gluconolactone 1 1995
* 5,571,841 Method of treating wrinkles using mandelic acid 4 1995
* 5,565,487 Method of treating wrinkles using galactonic acid or galactonolactone 2 1995
* 5,561,153 Method of treating wrinkles using mucic acid or mucolactone 1 1995
* 5,561,156 Method of treating wrinkles using methyllactic acid 1 1995
* 5,556,882 Methods of treating wrinkles using benzilic acid 1 1995
* 5,554,651 Method of treating wrinkles using citramalic acid 1 1995
* 5,550,158 Method of treating wrinkles using glucoheptonic acid 1 1995
* 5,942,250 Compositions and methods for enhancing the topical effects of sunscreen agents 7 1995
* 5,834,510 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 7 1995
* 5,690,967 Compositions for improved topical delivery of lactic acid 10 1995
* 5,691,378 Method for treating wrinkles using combinations of alpha hydroxyacids and/or alpha ketoacids 3 1995
* 5,686,489 Alpha hydroxyacid esters for skin aging 17 1995
* 5,684,044 Methods for improved topical delivery of lactic acid 3 1995
* 5,681,853 Methods for improved topical delivery of alpha hydroxyacids 6 1995
* 5,654,336 Methods of using glycolic acid for reversing or retarding the effect of aging on human facial skin 5 1995
* 5,571,837 Method of treating wrinkles using saccharic acid or saccharolactone 1 1995
* 5,561,158 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 13 1995
* 5,889,054 Method of using beta hydroxy acids for treating wrinkles 48 1997
* 5,962,526 Pharmaceutical compositions containing hydroxycarboxylic acids and/or ketocarboxylic acids and methods of using same 2 1997
* 5,856,357 Method for treating wrinkles using certain alpha hydroxyacids 4 1997
* 5,886,042 Amphoteric compostion and polymeric forms of alpha hydroxyacids, and their therapeutic use 67 1997
* 5,883,128 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use 7 1997
* 6,060,512 Method of using hydroxycarboxylic acids or related compounds for treating skin changes asociated with intrinsic and extrinsic aging 5 1998
* 6,051,609 Additives enhancing the effect of therapeutic agents 39 1998
6,384,079 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging 9 1999
* 6,191,167 Pharmaceutical compositions containing hydroxycarboxylic acid and/or ketocarboxylic acids and methods of using the same 13 1999
6,767,924 Method of using hydroxycarboxylic acids or related compounds for treating skin changes associated with intrinsic and extrinsic aging 56 2000
 
IOVATE HEALTH SCIENCES, INC. (1)
* 5,973,199 Hydrosoluble organic salts of creatine 15 1996
 
TRISTRATA, INCORPORATED (3)
RE41339 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use 7 2006
RE41278 N-acetyl aldosamines and related N-acetyl compounds, and their topical use 5 2006
RE42902 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use 1 2009
 
COSMEDERM TECHNOLOGIES (4)
7,404,967 Topical product formulations containing strontium for reducing skin irritation 5 2001
* 2003/0031,727 Topical product formulations containing strontium for reducing skin irritation 4 2001
8,147,855 Methods for inhibiting sensory responses in the skin such as pain and itch using topical product formulations containing strontium 0 2009
8,449,923 Methods for inhibiting sensory nerves by topically administering strontium-containing compositions to keratinized skin 0 2012
 
Neostrata Company, Inc. (1)
* 6,159,480 Cosmetic makeup composition 8 1997
 
KYOWA HAKKO BIO CO., LTD. (1)
* 2007/0191,485 Active oxygen scavenging composition including citrulline 1 2007
 
BAUSCH & LOMB INCORPORATED (1)
* 5,885,593 Skin care composition including cyclodextrin materials and method for treating skin therewith 15 1996
 
KYOWA HAKKO KOGYO CO., LTD. (1)
* 6,013,632 Compounds and their combinations for the treatment of influenza infection 19 1998
 
Dart Industries Inc. (1)
* 2004/0036,004 Adjustable mold for forming shaped food 0 2002
 
HYDRON TECHNOLOGIES, INC. (1)
* 5,879,684 Skin tightening formulation and method for treating skin 16 1997
 
REVLON CONSUMER PRODUCTS CORPORATION (2)
* 5,989,533 Hair conditioning compositions containing alpha or beta hydroxy acid esters 21 1997
* 6,080,390 Moisturizing cosmetic stick compositions 4 1999
 
KAO CORPORATION (2)
* 7,189,708 Topical composition for skin 0 2002
* 2003/0087,833 Topical composition for skin 0 2002
 
DORIT ARAD. (1)
* 6,888,033 Anti-viral compounds 1 1997
 
HAWKEYE-JENSEN, INC. (1)
* 6,448,251 Zwitterionic-fatty acid compounds having anti-inflammatory properties 0 2000
 
BASF BEAUTY CARE SOLUTIONS FRANCE SAS (1)
* 5,869,069 Lipophilic hydroxylated acid, its use in cosmetics and pharmacy, and its process of preparation 1 1996
 
EXEGENICS, INC., D/B/A OPKO HEALTH, INC. (1)
6,828,350 Modulators of cysteine protease 0 2000
 
OBAGI MEDICAL PRODUCTS, INC. (10)
7,927,614 Anti-aging treatment using copper and zinc compositions 1 2006
7,867,522 Method of wound/burn healing using copper-zinc compositions 0 2006
7,687,650 Chemical compositions and methods of making them 4 2006
* 2007/0191,620 Chemical compositions and methods of making them 6 2006
7,897,800 Chemical compositions and methods of making them 1 2007
* 2007/0203,354 Chemical Compositions and Methods of Making Them 9 2007
8,273,791 Compositions, kits and regimens for the treatment of skin, especially décolletage 0 2008
8,148,563 Chemical compositions and methods of making them 0 2010
9,427,397 Rosacea treatments and kits for performing them 0 2012
8,505,730 Compositions, kits and regimens for the treatment of skin, especially décolletage 0 2012
* Cited By Examiner