Controlled release dosage forms having a defined water content
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United States of America Patent
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Feb 25, 1992
Issued Date -
N/A
app pub date -
May 17, 1991
filing date -
Jun 2, 1988
priority date (Note) -
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Abstract
A controlled release, solid, oral dosage form containing a 3-alkylxanthine, preferably theophylline, at least one hydrophilic or hydrophobic polymer, at least one wax having a melting point between 25.degree. and 90.degree. C. and between 3% and 10% (by weight) water. Preferably the dosage form is a tablet and the water content is between 4% and 9% (by weight). The amount of water present in the dosage form determines the rate of release of the 3-alkylxanthine.
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