Production of a deoxyribonucleoside
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United States of America Patent
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Mar 3, 1992
Grant Date -
N/A
app pub date -
May 22, 1989
filing date -
May 31, 1988
priority date (Note) -
Expired
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Abstract
A process for the fermentative production of the deoxyribonucleoside thymidine and/or its corresponding base thymine by aerobically cultivating a strain of the genus Brevibacterium, in particular one of the strains NCIMB 40117 and 40116. The produced thymidine may be used as an intermediate in the production of azidothymidine and active ingredient in a composition for use in the treatment of auto imune deficiency syndrome (AIDS). Biologically pure cultures of strain NCIMB 40014 and variants and mutants derived therefrom are claimed per se.
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