Antisence oligonucleotides to c-myb proto-oncogene and uses thereof
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United States of America Patent
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Mar 24, 1992
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N/A
app pub date -
Oct 27, 1989
filing date -
Nov 7, 1988
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Abstract
Oligonucleotides are provided having a nucleotide sequence complementary to at least a portion of the mRNA transcript of the human c-myb gene. These 'antisense' oligonucleotides are hybridizable to the c-myb mRNA transcript. Such oligonucleotides are useful in treating hematologic neoplasms and in inducing immunosuppression. They are particularly useful as bone marrow purging agents.
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