Process for isolation and radiolabeling of pharmaceuticals with isotopes of astatine
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United States of America Patent
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Apr 7, 1992
Grant Date -
N/A
app pub date -
Dec 29, 1989
filing date -
Dec 29, 1989
priority date (Note) -
Expired
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Abstract
A process for recovering At-211 from a target and simultaneously producing an At-211-labeled radiopharmaceutical agent involves introducing volatilized At-211, produced by dry distillation of an irradiated Bi-209 target, into a solution containing a compound that binds the At-211 to form an At-211-labeled radiopharmaceutical agent. The radiopharmaceutical agent may have therapeutic use as is, or may be attached to a targeting protein such as an antibody prior to administation to a patient.
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