Method for reducing emesis and nausea induced by the administration of an emesis causing agent
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United States of America Patent
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Apr 7, 1992
Issued Date -
N/A
app pub date -
Jun 15, 1990
filing date -
Feb 17, 1989
priority date (Note) -
Expired
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Abstract
A method for preventing or relieving nausea and emesis associated with the use of an emesis-causing agent in warm-blooded animals comprises administering to the animal both a narcotic analgesic and a quaternary derivative of noroxymorphone prior to, simultaneously with of after administering the emesis-causing agent. A particularly preferred noroxymorphone derivative is methylnaltrexone. The method is highly effective in preventing or relieving nausea and emesis induced by anticancer drugs, and by apomorphine.
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