Bioadhesives for cell and tissue adhesion
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United States of America Patent
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Apr 28, 1992
Issued Date -
N/A
app pub date -
Apr 3, 1987
filing date -
Apr 25, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A cell culturing system, methods for the preparation thereof, and methods for affixing other biologically active moieties to a substrate are provided. Said cell culturing system comprises: a substrate; a coating thereon of a sterile formulation comprising polyphenolic protein containing from about 35 to 100% by weight pure bioadhesive polyphenolic protein having the repeating decapeptide unit: ##STR1## wherein N is a whole number ranging from about 10 to about 100, wherein each X is independently selected from the group consisting of hydroxyl and hydrogen, and wherein each R is independently selected from the group consisting of hydrogen and methyl; viable cells affixed to said coated substrate; and a nutritive medium contacting said cells, whereby said cells perform normal metabolic cell functions.
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