Radiolabeled proteins for diagnostic or therapeutic use

United States of America Patent

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May 12, 1992
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N/A
app pub date
Dec 29, 1989
filing date
Dec 29, 1989

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Expired

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Abstract

Chelating compounds of specified structure are useful for radiolabeling targeting molecules such as antibodies. Cleavable linkers connect the radionuclide metal chelates to the antibodies. The radiolabeled antibodies have improved biodistribution properties, including reduced localization within the intestines and kidneys.

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Patent Owner(s)

Patent Owner	Address
NEORX CORPORATION A CORP OF WA	410 WEST HARRISON SEATTLE WA 98119

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C07K:PEPTIDES

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[Patents Count]

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Inventor Name	Address	# of filed Patents	Total Citations
Fitzner, Jeffrey N	Seattle, WA	12	280
Gustavson, Linda M	Seattle, WA	34	497
Jones, David S	Seattle, WA	64	857
Kasina, Sudhakar	Kirkland, WA	56	1242
Reno, John M	Brier, WA	58	3239
Srinivasan, Ananthachari	Kirkland, WA	50	1281

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Radiolabeled proteins for diagnostic or therapeutic use

Number of patents in Portfolio can not be more than 2000

United States of America Patent

07457480

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PATENT NO	5112953
SERIAL NO	07457480
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07457480

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