Process for the production of permanently culturable animal and human cell lines and the use thereof

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United States of America Patent

PATENT NO 5114847
SERIAL NO

07590602

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Abstract

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A method for obtaining permanently culturable human and animal cell lines, as well as uses for these cell lines, are disclosed. The method involves fusing cells of a non-immortal cell line with cytoplasts or cytoplasma fractions of 'immortal', transformed cells such as immortal myeloma cells, ascites-tumor cells or Epstein Barr Virus infected cells. Once fusion takes place the product is a permanently culturable variant of the previously normal cell line.

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Patent Owner(s)

  • BOEHRINGER MANNHEIM GMBH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albert, Winfried Pahl, DE 37 731
Barchet, Heinrich Tutzing, DE 5 24
Jungfer, Herbert Tutzing, DE 11 155

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