Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
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United States of America Patent
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Jun 30, 1992
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N/A
app pub date -
Aug 10, 1990
filing date -
Nov 16, 1988
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Expired
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Abstract
A process and compositons for reducing post-surgical adhesion formation/reformation in mammals following injury to organs situated in mammalian body spaces. Aqueous, thermally reversible gel compositions, preferably at mammalian body fluid pH, comprising a polyoxyalkylene polymer and an ionic polysaccharide are applied to injured areas of the organs situated in body cavities such as, the peritoneal, pelvic, or pleural cavity. The aqueous gels are rendered thermally irreversible upon contact with a counter-ion.
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