Aldophosphamide glycosides, a process for their preparation and their use as pharmaceutical active compounds
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United States of America Patent
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Jun 30, 1992
Grant Date -
N/A
app pub date -
Jun 7, 1989
filing date -
Jun 9, 1988
priority date (Note) -
Expired
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Abstract
Compounds of the formula ##STR1## in which R.sup.1 represents saturated, unsaturated or anhydro desoxypentosyl, desoxyhexosyl or didesoxyhexosyl, where the OH functions of the sugar are optionally protected, and R.sup.2 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms and R.sup.3 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms and X represents halogens and R.sup.4 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms. Such compounds are useful as highly selective cytostatics in cancer therapy.
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