Transdermal therapeutic system for active ingredient combinations
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United States of America Patent
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Jul 7, 1992
Issued Date -
N/A
app pub date -
Feb 22, 1991
filing date -
Apr 2, 1987
priority date (Note) -
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Abstract
The present invention relates to a transdermal therapeutic system for the combined administration of oestrogens and gestagens. The therapeutic system consists of: (1) a closed outer layer which is impermeable to the constituents of the active ingredient formulation, (2) a reservoir containing essential constituents of the active ingredient formulation and, optionally, a membrane, (3) an adhesive layer and (4) a peel-off protective layer on the adhesive layer. The system contains an oestrogen derivative in combination with a synthetic gestagen, and an agent that enhances percutaneous absorption.
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