Factor-dependent hematopoietic cell line exhibiting epo-induced erythrocyte maturation
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United States of America Patent
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Jul 7, 1992
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N/A
app pub date -
Oct 27, 1989
filing date -
Oct 27, 1989
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Abstract
Factor-dependent cell line, HU-01, provides the first in vitro system in which human CD34 positive hematopoietic cells have been induced to undergo complete differentiation into enucleated hemoglobin-containing erythrocytes. HU-01 cells may provide a source of monoclonal antibodies useful for early diagnosis and possible treatment of human leukemia conditions, as well as of regulatory factors having therapeutic utility.
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