Synthetic peptide antagonists of neurokinin A, salts thereof and respective preparation processes
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United States of America Patent
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Jul 7, 1992
Grant Date -
N/A
app pub date -
May 24, 1990
filing date -
May 29, 1989
priority date (Note) -
Expired
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Abstract
A synthetic peptide corresponding to the following formula: X--Asp--Y--DTrp--Val--DTrp--Z--K--NH.sub.2 where: X=H, Arg, DArg, Lys, DLys, Thr, DThr Y=Tyr, Trp, DTrp, Ser, Met Z=Trp, DTrp K=Arg, Phe, DTrp, Tyr, Met and pharmaceutically acceptable salts thereof with organic and inorganic acids as competitive antagonists against neurokinin A (NK-2 receptor).
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