Boronated nucleoside, nucleotide and oligonucleotide compounds, compositions and methods for using same
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United States of America Patent
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Jul 14, 1992
Grant Date -
N/A
app pub date -
Dec 20, 1989
filing date -
Dec 20, 1989
priority date (Note) -
Expired
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Abstract
A novel class of pharmaceutically active boronated nucleosides are provided. The nucleosides are boronated at a ring nitrogen of the purine or pyrimidine or analogues thereof. Also provided are phosphate esters of these nucleosides and oligomers thereof. Methods of making and using the boronated nucleosides are also disclosed.
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