Methods of treating disorders which cause conglutinin deficiency
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United States of America Patent
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Jul 21, 1992
Issued Date -
N/A
app pub date -
Nov 27, 1989
filing date -
Dec 10, 1985
priority date (Note) -
Expired
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Abstract
Human conglutinin, polyclonal, and monoclonal antibodies raised against human conglutinin, and their uses in therapy and diagnosis are described. Human conglutinin was obtained from human plasma by affinity chromatography with anti-bovine conglutinin antibody, has a relative molecular weight of 330 and 40 K unreduced and 66 K reduced as measured by SDS-PAGE, shows calcium-dependent and sugar inhibitable binding to complement-reacted immune complexes and zymosan, and immunological cross-reaction with anti-bovine conglutinin antibody.
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