Method and apparatus for monitoring blood analytes noninvasively by pulsatile photoplethysmography
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United States of America Patent
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Aug 11, 1992
Grant Date -
N/A
app pub date -
Apr 19, 1990
filing date -
Apr 19, 1990
priority date (Note) -
Expired
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Abstract
A non-invasive system for measuring the concentration of an analyte, such as glucose, in an absorbing matrix is described. The system directs beams of light at the matrix using an analyte sensitive wavelength and an analyte insensitive wavelength. The principles of photoplethysmography are applied to measure the change in light intensity caused by matrix absorption before and after the blood volume change caused by the systolic phase of the cardiac cycle. The change in light intensity is converted to an electrical signal which is used to adjust the light intensity and as a measure of analyte concentration.
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